Guide for Authors. Editorial policies

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1 Guide for Authors Regional Anesthesia and Pain Medicine, official publication of the American, European, Asian and Oceanic, and Latin American Societies of Regional Anesthesia, is a bimonthly peer-reviewed journal providing scholarly presentation of science and clinical issues of importance to anesthesiologists and other physicians engaged in regional anesthesia and pain medicine. It publishes original articles, case reports, history articles, imaging articles, informatics articles, review articles, special articles, translational vignettes, editorials, book reviews, and letters to the editor. Three or more members of the Editorial Board or outside consultants review all manuscripts except for correspondence. NOTE: Regional Anesthesia and Pain Medicine now uses Editorial Manager Submission and Peer Review System, an Internet-based system for the submission of all incoming manuscripts. To submit a manuscript, visit If you are not registered with the system, click on 'Register' at the menu at the top of the page and proceed as instructed. Then click on 'Submit' and follow the instructions to upload the various elements of your submission, eg, the text, figures, etc. For all queries, including questions about how to use the system, authors may e- mail the editorial office at rapm@vmmc.org or call (206) Editorial policies Originality: Manuscripts and all materials are received with the understanding that they have not been published, or are under consideration for publication, in whole or in any significant part elsewhere, and a Cover Letter (see Manuscript Submission Cover Letter below) to this effect should be enclosed with all materials. Therefore, no substantial part of a paper may have been published elsewhere, except for a scientific abstract. If one has a concern or is in question concerning prior publication, please submit the title page and abstract with submission of materials. Data Analysis: Manuscripts and all materials are received with the understanding that each author listed has participated in the conception, design, execution, and/or analysis of data (as applicable), as well as the writing of the manuscript. The signatories to the Cover Letter attest to the accuracy and validity of the manuscript contents and are listed as authors or otherwise acknowledged for their contributions. Authorship: Manuscripts and all materials are received with the understanding that all signatories to the Cover Letter have reviewed the submission and approve its submission for publication. No additional editing from the author(s) may occur once the manuscript and all materials are received at the editorial office. Copyright: All authors must sign a copy of the Journal's "Authorship Responsibility, Financial Disclosure, and Copyright Transfer" form (see Copyright Transfer Agreement below) in acceptance for publication. Compliance with NIH and Other Research Funding Agency Accessibility Requirements: A number of research funding agencies now require or request authors to submit the post-print (the article after peer review and acceptance but not the final published article) to a repository that is accessible online by all without charge. As a service to our authors, the publisher, Lippincott Williams & Wilkins, will identify to the National Library of Medicine articles that require deposit and will transmit the post-print of an article based on research funded in whole or in part by the National Institutes of Health, Wellcome Trust, Howard Hughes Medical Institute, or other funding agencies to PubMed Central. The journal s Copyright Transfer agreement provides the mechanism. Cover Letter and Check List: A Manuscript Submission Cover Letter (see below) and Manuscript

2 Check List (see below) must accompany all submissions. The Cover Letter must contain the following language before the materials can be received: "In consideration of Regional Anesthesia and Pain Medicine taking action in reviewing and editing my (our) submission, the author(s) undersigned hereby transfers, assigns, or otherwise conveys all copyright ownership to the American Society of Regional Anesthesia and Pain Medicine in the event that such work is published by Regional Anesthesia and Pain Medicine." The Cover Letter should name one author as correspondent (with address, telephone, Fax, and e- mail) and include the signatures of all the authors, which signifies that each listed author must: (1) have participated in the work and could publicly defend its contents, and (2) have read the manuscript prior to its submission for publication and agree with its contents. No submission will enter the review process until all authors have undersigned the Cover Letter. If a manuscript is accepted for revision, the author must submit an "Authorship Responsibility, Financial Disclosure, and Copyright Transfer" form (see Copyright Transfer Agreement below) with the revised manuscript. The authorship/copyright transfer form must accompany all manuscripts accepted for publication. Manuscripts will not be published without completion of the form at final acceptance. Peer-Review Process: Following the successful uploading of a manuscript into the journal s Editorial Manager online submission system, an acknowledgement will be provided immediately to the corresponding author. Then authors are usually advised within 8 weeks if their manuscript has been accepted, rejected, or requires revision before acceptance. All revisions will require a final decision; resubmission does not guarantee acceptance of the revision. Unforeseen delays may occur and are unavoidable (for example: if a manuscript is sent for additional review of statistics); should this happen it is customary for the editorial office to contact the author. An author may check the status of their submission at any time by logging on to Ethical concerns Patient Identification: Patients' names, initials, hospital numbers, and admission case dates are to be avoided in all materials. In addition, a patient must not be recognizable in any photograph unless written permission of the subject has been provided and is included with the submission. Human Trials: No manuscript describing investigations carried out in humans will be accepted for publication unless the text states that the study was approved by the author's institutional human investigation committee and that informed consent was obtained from all subjects or, in the case of minors, from parents. A statement regarding Institutional Review Board (IRB) approval and procedures is required and must be clearly stated in the Methods section. Animal Studies: No manuscript describing investigations in animals will be accepted for publication unless the text states that the author's institutional animal investigation committee approved the study. IRB approval must be stated and/or final approval included. Funding Sources: Authors are required to indicate all sources of funding supporting their submission. This does include any corporate or institutional funding sources. Conflicts of Interest: Authors are required to state clearly on the Check List any conflicts of interest associated with their submitted work. This includes consultancies and licensing arrangements.

3 Submission categories Original Article: Describes a clinical or laboratory investigation. Case Report: Describes any new or instructive cases, anesthetic or pain medicine techniques, or equipment that is original. History Article: Provides a historical perspective of the heritage of regional anesthesia or pain medicine. May be focused around individuals or concepts. Imaging Article: Describes any new or instructive material using imaging techniques applicable to regional anesthesia or pain medicine settings. Evidence-Based Case Report: Describes the presentation of one or more case reports of a common regional anesthesia or pain management scenario, followed by a detailed literature review and analysis aimed at describing evidence-based "best practice." Review Article: Provides comprehensive coverage of previously published material to aid in the evaluation of important or new concepts. Authors interested in submitting a review article should send a cover letter identifying the topic and an outline of their proposal to the Editor in Chief: Joseph.Neal@vmmc.org. Special Article: Describes unique topics or trends relevant to regional anesthesia and pain medicine. Translational Vignette: Describes relevant basic science topics that are translated in clinical terms for physicians in the fields of regional anesthesia and pain medicine. Editorial (solicited by the Editorial Board): Comments on articles published in Regional Anesthesia and Pain Medicine and provides relevant information for regional anesthesiologists or those in pain medicine. Book Review: Reports on current literature relevant to the areas of regional anesthesia and pain medicine. All books and multimedia material for review should be sent directly to: Joseph M. Neal, M.D., Editor in Chief, Regional Anesthesia and Pain Medicine, Virginia Mason Medical Center, Mailstop D2-APM, 1100 Ninth Avenue, Seattle, WA Letter to the Editor: Provides brief constructive commentary on previously published articles or information of general interest. Manuscript preparation Style: Manuscripts must be prepared and submitted in the manner described in the American Medical Association Manual of Style. Formatting: All materials (title, abstract, text, references, tables, appendices, and legends) must be in English and should be double-spaced. Fonts should be at least 10 point or larger in a Times New Roman style. A font size of 12 points is requested. Provide margins of 1 inch (2.5 cm) at top, bottom, left, and right sides of all pages. The page number should appear in the upper right-hand corner of each page, beginning with the Title Page. Please number pages consecutively and begin each section on a new page in sequence (title page, abstract, text, references, tables, legends for illustrations, and illustrations).

4 Organization: The manuscript should be arranged in this order: Title Page, Abstract, Text, References, Tables, Legends for Illustrations, and Illustrations. Please observe the following maximum limitations for each submission category. Submission Category Text (double-spaced pages) Figures & Tables (number) References (number) Original Article Case Report Brief Technical Report History Article Imaging Article Evidence-Based Case Report Review Article Special Article Translational Vignette Editorial 4-10 Book Review Letter to the Editor Title page (page 1) All submissions must contain a Title Page indicating the title of the article. The title must be succinct and informative to the reader. The names of the authors and their highest degrees and departmental/institutional affiliations must appear on the Title Page. List the first name, middle initial, and last name of each author, with highest academic degree(s) and institutional affiliation. The principal author must justify listing more than five authors in the Cover Letter. Provide the name, full mailing address, telephone number, Fax number, and address of the corresponding author on the Title Page. Provide the name of the department(s) and institution(s) to which the work should be attributed. Identify financial sources that supported the work. Indicate any meetings where the work may have been presented. Provide a running head of no more than 45 characters (including text and spaces) on the Title Page. Abstract Original article Provide an abstract of no more than 250 words with headings of Background and Objectives,

5 Methods, Results, and Conclusions. Do not include abbreviations, footnotes, or references in the Abstract. Background and Objectives: State the main question or objective of the study and major hypothesis tested, if any. Methods: Describe the study design, indicating, as appropriate, use of randomization, blinding, criterion standards for diagnostic tests, temporal direction (retrospective or prospective), and so on. The primary study outcome measures should be indicated as planned before data collection began. If the hypothesis being reported was formulated during or after data collection, this fact should be clearly stated. Results: Describe measurements that are not evident from the nature of the main results and indicate any blinding. If possible, the results should be accompanied by confidence intervals (most often the 95% interval) and exact level of statistical significance. For comparative studies, confidence intervals should be indicated when risk changes or effect sizes are given. Conclusions: State only those conclusions of the study that are directly supported by data, along with their clinical application (avoiding overgeneralization) or whether additional studies are required before the information should be used in the clinical setting. Equal emphasis must be given to the positive and negative of equal merit. Key Words: Provide an alphabetical list of no more than six key words. These words should be simple and will be used for indexing. Abstract Case report Provide an abstract of no more than 250 words with headings of Objective, Case Report, and Conclusions. Do not include abbreviations, footnotes, or references in the Abstract. Objective: State the primary objective of the case report. Case Report: Briefly describe important details of the case report. Conclusions: State the main conclusion from the case description. Key Words: Provide an alphabetical list of no more than six key words. These words should be simple and will be used for indexing. Abstract History article The abstract for the history articles will only include the Introduction. Introduction: Use one or two sentences to develop the historical issue to be presented. Key Words: Provide an alphabetical list of no more than six key words. These words should be simple and will be used for indexing.

6 Text Original article Text for original articles is usually divided into sections with the headings of: Introduction, Methods, Results, Discussion, Acknowledgments. Introduction (new page): Clearly state the article s purpose. Give only pertinent references, and do not review the subject extensively. Methods (new page): Describe clearly your selection of observational or experimental subjects. Identify methods, apparatus, and procedures in enough detail to allow others to reproduce the results. Results (new page): Present your results in a logical sequence in text, tables, and illustrations. Emphasize or summarize only important observations. Discussion (new page): Emphasize new and important aspects of the study and conclusions that follow from them. Acknowledgments (new page): Acknowledge only individuals who have made substantive contributions to the study. Text Case report Text for case reports is usually divided into sections with the headings of Introduction, Case Report, and Discussion. Introduction (new page): Briefly summarize why this case demands review. Case Report (new page): Provide sufficient details of the patient case study to allow readers to understand the decision making used in providing care. Discussion (new page): Emphasize new and important understandings that were learned from this case and conclusions that follow from them. Text Letter to the editor The text for letters to the editor should follow a letter format. References The references selected for inclusion in a manuscript must be relevant to the work described. Reference citations must be to books or articles and abstracts published in peer-reviewed PubMed/Index Medicus journals. Please do not include referenced articles published without peer review. This includes abstracts or articles printed in meeting materials or societal publications. Abstracts appearing more than 3 years ago are not acceptable. All references cited in the manuscript must be available to all readers. Manuscripts in preparation or submitted for peer

7 review are not acceptable as references. Articles that have been accepted but not yet published may be cited provided that the "in press" manuscript is included with the submission. Numbering: Number references consecutively in the order which they are cited in the text, tables, and legends. Formatting: Double-space between all lines of each reference and between references. Identifying: Use Arabic numerals (in parentheses, on line) to identify references in text, tables, and legends. Accuracy: Verify all references against their original published source. Style: Abbreviate journal titles according to the style found in Index Medicus. The style of references must be based on the format used by the US National Library of Medicine in Index Medicus. Standard journal article (List all authors up to 6; if more than 6, list 3 and et al. ): Hurley RW, Lesley MR, Adams, MCB, Brummett CM, Wu CL. Pregabalin as a treatment for painful diabetic peripheral neuropathy: A meta-analysis. Reg Anesth Pain Med 2008;33: Entire book: Barash PG, Cullen BF, Stoelting RK, Cahalan M, Stock MC: Clinical Anesthesia. 6 th ed. Philadelphia, PA: Lippincott Williams & Wilkins, Chapter in a book: Goldhaber-Fiebert S, Cooper JB. Safety in anesthesia. In: Dunn PF, Alston T, Baker K, Davison JK, Kwo J, Rosow C. Clinical Anesthesia Procedures of the Massachusetts General Hospital. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins, Tables Numbering: Number tables consecutively in the order cited in the text using Arabic numerals (Table 1, Table 2, etc.). Formatting: Type each table on a separate sheet, double-spaced. Supply a brief title for each table. Provide each column with a short or abbreviated heading. Tables submitted as photographs are not acceptable. Do not repeat information in a table if data is already provided in the text or do not prepare a table for data that is not reported in the text in one or two sentences. Footnotes: Put explanatory matter in footnotes, not in the table title or column heading. Please define all abbreviations used in each table in the footnotes. Permissions: If a table or its data is reproduced from another source, the author is responsible for securing permission for both print and electronic rights from the original publisher and is responsible for paying any permission fees. Cite the original source of previously published material following the wording specified in the publisher s permission letter.

8 Legends for illustrations Numbering: Number figures consecutively in the order cited in the text, using Arabic numerals (Fig 1, Fig 2, etc.). If a figure contains more than one part, each part must be labeled alphabetically (Fig 3A, Fig 3B, etc.). Formatting: Provide a legend for each figure. Type legends double-spaced on a separate manuscript page. Identification: Explain clearly in the legend any symbols, arrows, numbers, or letters used to identify parts of the figure. Identify the method of staining in photomicrographs and provide their magnifications. Abbreviations: In the figure legends, define all abbreviations used in each illustration. Permissions: If a figure or its data is reproduced from another source, the author is responsible for securing permission for both print and electronic rights from the original publisher and is responsible for paying any permission fees. Cite the original source of previously published material following the wording specified in the publisher s permission letter. Illustrations Digital figures: Electronic art should be created/scanned and saved and submitted as a TIFF (tagged image file format) or an EPS (encapsulated postscript) file. Use of PPT (PowerPoint) files is not recommended. If PPT files are the only available file format, please follow the instructions at to convert to publication-quality images. Line art must have a resolution of at least 1200 dpi (dots per inch), and electronic photographs radiographs, CT scans, and so on and scanned images must have a resolution of at least 300 dpi. If fonts are used in the artwork, they must be converted to paths or outlines or they must be embedded in the files. Color images must be created/scanned and saved and submitted as CMYK files. Please note that artwork generated from office suite programs such as Corel Draw and MS Word and artwork downloaded from the Internet (JPEG or GIFF files) cannot be used. All electronic art that cannot be successfully uploaded must be submitted on a 3½-inch high-density disk, a CD-ROM, or an Iomega Zip disk, accompanied by high-resolution laser prints of each image. Further information on preparing digital artwork for publication can be found at Color Images: Submit illustrations in color only if the use of color is crucial. Color illustrations will be published only at the author's expense, but the Editor reserves the right to publish at no expense to the author. Formatting: Line drawings should be professionally executed and photographed, with lettering large enough to be easily read after necessary reduction. Line art should be

9 submitted with no gradations of shading, as they will not reproduce for clarity. Use crosshatching or patterns where shading is necessary. Patient Consent: If a figure contains a human subject that is identifiable, written consent from the patient or guardian must accompany the submission. Reprints Authors will receive a reprint order form and price list with their page proofs. Reprint requests should be faxed with the corrected proofs, if possible. Reprints are shipped 6 to 8 weeks after publication of the issue in which the article appears. For questions, contact the Reprint Department, Lippincott Williams & Wilkins, 351 W. Camden Street, Baltimore, MD 21201; Fax: ; e- mail: reprints@wolterskluwer.com. Publisher's contact Fax corrected page proofs, reprint order forms, and any related materials to: RAPM Production Editor, Regional Anesthesia and Pain Medicine, , or by mail to: RAPM Production Editor, Regional Anesthesia and Pain Medicine, Lippincott Williams & Wilkins, 351 W. Camden Street, Baltimore, MD USA. Manuscript Submission Cover Letter (must accompany all initial submissions) Name of Corresponding Author: Address of Corresponding Author: Telephone Number: Fax Number: Address: Date of Submission: Joseph M. Neal, M.D. Editor in Chief, Regional Anesthesia and Pain Medicine Virginia Mason Medical Center MSC D2-APM th Avenue Seattle, WA UNITED STATES Dear Dr. Neal: Re (Title of Manuscript): I (we) are submitting the enclosed material for possible publication in Regional Anesthesia and Pain Medicine. This material has not been submitted for publication or published elsewhere in

10 whole or part. The undersigned listed have participated in the work and can publicly defend the manuscript s contents, and have read the manuscript prior to its submission for publication and agree with its contents. In consideration of Regional Anesthesia and Pain Medicine taking action in reviewing and editing my (our) submission, the author(s) undersigned hereby transfers, assigns, or otherwise conveys all copyright ownership to the American Society of Regional Anesthesia and Pain Medicine in the event that such work is published by Regional Anesthesia and Pain Medicine. No submission will enter the review process until all authors have signed this Cover Letter. Printed Name Signature Date Printed Name Signature Date Printed Name Signature Date Printed Name Signature Date Printed Name Signature Date Printed Name Signature Date Manuscript Submission Check List (must accompany all initial submissions) Manuscript Submission Cover Letter with signatures Title Page Title List each author: first name, middle initial, last name, highest degree credentials, and institutional affiliations Corresponding author: as above, and include complete mailing address, telephone number, Fax number, and address Identification of institution(s) where work is attributed Identification of financial source(s) which support the work Identification of any meetings where the work may have been presented Identification of a running head (45 characters or less) Abstract (250 words or less) Background and Objectives

11 Methods Results Conclusions Key Words (6 or less) Text Introduction Methods Results Discussion Acknowledgments References Copies of any In-Press Papers Tables Legends for figures Figures Conflicts of Interest (list below) Electronic File(s)

12 Copyright Transfer Agreement Regional Anesthesia and Pain Medicine Authorship Responsibility, Financial Disclosure, and Copyright Transfer Manuscript Title: (the Work ) Corresponding Author: Mailing Address and Telephone/Fax Numbers: Each author must read and sign the following statements; if necessary, photocopy this document and distribute to coauthors for their original ink signatures. Completed forms should be submitted to the Editorial Office with the Work or returned to: Jeffrey Baker, Managing Editor, Regional Anesthesia and Pain Medicine, Virginia Mason Medical Center, MSC D2-APM, th Avenue, Seattle, WA rapm@vmmc.org. CONDITIONS OF SUBMISSION RETAINED RIGHTS: Except for copyright, other proprietary rights related to the Work (e.g., patent or other rights to any process or procedure) shall be retained by the authors. To reproduce any text, figures, tables, or illustrations from this Work in future works of their own, the authors must obtain written permission from Lippincott Williams & Wilkins (LWW); such permission cannot be unreasonably withheld by LWW. ORIGINALITY: Each author warrants that his or her submission to the Work is original and that he or she has full power to enter into this agreement. Neither this Work nor a similar work has been published nor shall be submitted for publication elsewhere while under consideration by this Publication. AUTHORSHIP RESPONSIBILITY: Each author warrants that he or she has participated sufficiently in the intellectual content, the analysis of data, if applicable, and the writing of the Work to take public responsibility for it. Each has reviewed the final version of the Work, believes it represents valid work, and approves it for publication. Moreover, should the editors of the Publication request the data upon which the work is based, they shall produce it. DISCLAIMER: Each author warrants that this Work shall not violate any trademark registrations nor the right of privacy of any person, contains no libelous, obscene, or other unlawful matter, and does not infringe upon the statutory or common law copyright or any other right of any person or party. If excerpts (text, figures, tables, or illustrations) from copyrighted works are included, a written release will be secured by the authors prior to submission, and credit to the original publication will be properly acknowledged. Each author further warrants that he or she has obtained, prior to submission, written releases from patients whose names or photographs are submitted as part of the Work. Should LWW request copies of such written releases, authors shall provide them to LWW in a timely manner. PREPRINTS: Upon acceptance of the article for publication, each author warrants that he/she will promptly remove any prior versions of this work (normally a preprint) that may have been posted to an electronic server. TRANSFER OF COPYRIGHT AUTHORS OWN WORK: In consideration of LWW s publication of the Work, the authors hereby transfer, assign, and otherwise convey all copyright ownership worldwide, in all languages, and in all forms of media now or hereafter known, including electronic media such as CD-ROM, Internet, and Intranet, to LWW. If LWW should decide for any reason not to publish an author s submission to the Work, LWW shall give prompt notice of its decision to the corresponding author, this agreement shall terminate, and neither the author nor LWW shall be under any further liability or obligation. Each author grants LWW the rights to use his or her name and biographical data (including professional affiliation) in the Work and in its or the Publication s promotion. WORK MADE FOR HIRE: If this work has been commissioned by another person or organization, or if it has been written as part of the duties of an employee, an authorized representative of the commissioning organization or employer must also sign this form stating his or her title in the organization. GOVERNMENT EMPLOYEES: If this submission to the Work has been written in the course of any author s employment by the United States Government, check the Government box at the end of this form. A work prepared by a government employee as part of his or her official duties is called a work of the U.S. Government and is not subject to copyright. If it is not prepared as part of the employee s official duties, it may be subject to copyright. FINANCIAL DISCLOSURE: Each author warrants that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article, except as disclosed on a separate attachment. All funding sources supporting the Work and all institutional or corporate affiliations of the authors are acknowledged in a footnote in the Work. INSTITUTIONAL REVIEW BOARD/ANIMAL CARE COMMITTEE APPROVAL: Each author warrants that his or her institution has approved the protocol for any investigation involving humans or animals and that all experimentation was conducted in conformity with ethical and humane principles of research. AUTHOR(S) POSTING OF ARTICLES TO AN INSTITUTIONAL REPOSITORY Regional Anesthesia and Pain Medicine will permit the author(s) to deposit for display a post-print (the final manuscript after peerreview and acceptance for publication but prior to the publisher s copyediting, design, formatting, and other services) 12 months after publication of the final article on his/her personal web site, university s institutional repository or employer s intranet, subject to the following: You may only deposit the post-print. You may not update the post-print text or replace it with a proof or with the final published version. You may not include the post-print or any other version of the article in any commercial site or in any repository owned or operated by any third party. For authors of articles based on research funded by NIH, Wellcome Trust, HHMI, or other funding agency, see below for the services that LWW will provide on your behalf to comply with "Public Access Policy" guidelines.

13 You may not display the post-print until twelve months after publication of the final article. You must attach the following notice to the post-print: This is a non-final version of an article published in final form in (provide complete journal citation). You shall provide a link in the post-print to Regional Anesthesia and Pain Medicine s website.

14 PUBLIC ACCESS POLICY FUNDING DISCLOSURE Please disclose below if you have received funding for research on which your article is based from any of the following organizations: National Institutes of Health (NIH) Wellcome Trust Howard Hughes Medical Institute (HHMI) Other: Please List COMPLIANCE WITH NIH AND OTHER RESEARCH FUNDING AGENCY ACCESSIBILITY REQUIREMENTS A number of research funding agencies now require or request authors to submit the post-print (the article after peer review and acceptance but not the final published article) to a repository that is accessible online by all without charge. Within medical research, three funding agencies in particular have announced such policies: The U.S. National Institutes of Health (NIH) requires authors to deposit post-prints based on NIH-funded research in its repository PubMed Central (PMC) within twelve months after publication of the final article in the journal. The Howard Hughes Medical Institute (HHMI) requires as a condition of research grants, deposit in PMC, but in its case within six months after publication of the final article. The Wellcome Trust requires, as a condition of research grants, deposit in UK PubMed Central within six months after publication of the final article. As a service to our authors, LWW will identify to National Library of Medicine (NLM) articles that require deposit. This Copyright Transfer Agreement provides the mechanism for identifying such articles. LWW will transmit the post-print of an article based on research funded in whole or in part by one or more of these three agencies to Pub Med Central. Upon NIH request, it remains the legal responsibility of the author(s) to confirm with NIH the provenance of their manuscript for purposes of deposit. Author(s) will not deposit their articles themselves. Author(s) will not alter the post-print already transmitted to NIH. Author(s) will not authorize the display of the post-print prior to: (a) 12 months following publication of the final article, in the case of NIH, (b) 6 months following publication of the final article, in the case of Wellcome Trust and HHMI Signature Printed Name Date Author s Own Work Work for Hire Government Financial Disclosure Attached Signature Printed Name Date Author s Own Work Work for Hire Government Financial Disclosure Attached Signature Printed Name Date Author s Own Work Work for Hire Government Financial Disclosure Attached Signature Printed Name Date Author s Own Work Work for Hire Government Financial Disclosure Attached Signature Printed Name Date Author s Own Work Work for Hire Government Financial Disclosure Attached

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