leading the wave E 3 System Desktop Visual Electrophysiology System

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1 leading the wave E 3 System Desktop Visual Electrophysiology System

2 E 3 with LCD Monitor System Our advanced high brightness and fast response monitors are custom engineered to enable very effective clinical diagnostic testing E 3 consoles are paired with performance LCD monitors and integrated patient chin rest 32-Bit Amplifier Fixation Cameras Pattern Stimulator Unprecedented 1 nano Volt resolution and illuminated receptacles guide lead insertion and electrode contact quality Diagnosys offers a selection of high performance fixation monitoring cameras that integrate with Espion software Fully compliant ISCEV standard PERG and pvep are delivered using the miniature OLED monitor which

3 E 3 with ColorDome System he world's leading Ganzfeld stimulator, ColorDome has a trillion-to-1 luminance range and flash durations from nanoseconds to hours E 3 with ColorDome features: Most compact Desktop system Integrated monitoring camera Regular and Operating Room arms Performance Leader Unmatched repeatability; ERG responses from 15 different systems 1 ColorBurst Handheld Ganzfeld stimulator option; enables optimal Pediatric and Operating Room ERG testing ColorDome Modules Optional modules further expand system value: Pupillometry Dark adaptation Scotopic threshold 1 Rustum Karanjia, Martin W. ten Hove and Stuart G. Coupland (2011). Electroretinograms and ormative Data, Electroretinograms, Dr. Gregor Belusic (Ed.), Inech, DOI: /23387.

4 E 3 System Desktop visual electrophysiology system leading the wave E 3 Features 3 rd Generation advanced performance All visual electrophysiology tests possible Industry leading 32-bit amplifiers: <1 ano-volt resolution ColorDome has a trillion-to-1 luminance range Unprecedented ERG repeatability Modular, full features, easy to use 5 powerful stimulators you can mix & match Most cost effective, compact system on the market Set up system and initiate testing in hours Unique, electrode testing amplifier speeds patient set-up Most widely used system world-wide E 3 console, 32-bit amplifier, computer and Espion software. Choose from the broadest range of stimulators in the industry: Stimulator ColorDome ColorBurst Performance LCD 19 CR Envoy Mini Pattern Stimulator Primary use Applications Configuration options Protocols Ganzfeld full-field ERG and EOG Pediatric, OR, handheld Ganzfeld Multi-focal ERG Pattern ERG, VEP Pattern ERG, VEP Full range of retina functional test: clinical diagnostics, clinical trials, clinical safety studies, Stem cell & genetic research, euro-ophthalmology, R&D, advanced diagnostics abletop, Operating Room, floor stand ISCEV full-field ERG (6 tests) With or without stand ISCEV full-field ERG (6 tests) Dark-adapted 30 ERG Dark-adapted 30 ERG Long duration flash Long duration flash Uniform field PERG Flash Visual Evoked Potential (VEP) Flash VEP With or without chin rest ISCEV multi-focal ISCEV PERG ISCEV PERG ERG (mferg) Pattern VEP* ISCEV mferg Multi-focal ERG Multi-focal PhR (mfphr) ISCEV VEP ISCEV Pattern VEP ISCEV Pattern VEP Uniform field PERG Uniform field PERG Uniform field PERG mfvep Sweep VEP** Photopic negative PhR Uniform field response (PhR) PERG Scotopic threshold response Double flash ERG EOG Pupillometry Fast scotopic threshold Other: see ColorDome brochure Scotopic threshold response Double flash ERG Other: see ColorBurst brochure Multi-focal VEP** Sweep VEP** otes: 1) *on-iscev standard protocol; 2) **currently in development at Diagnosys mfphr

5 System specifications E 3 Console Advanced real-time acquisition system with integrated power isolation Direct pattern generator Isolated auxiliary line outlets to meet medical leakage current standards All-digital filtering Hardened, machined aluminum case Amplifier Full DC 2-channel, fully differential, 32-bit amplifiers have 1 nano Volt resolution, which provide the highest resolution in the industry; ultra low noise 5 Volt input range, ensures amplifier will not over-range Common mode rejection: >100 db Stimulators Refer to individual stimulator brochures Computer Desktop all-in-one computer or ablet computer; Runs on Windows 7 through 10 Espion Software Automatic rejection Peak/trough detect & measure SQL relational database Multiple operator modes Cameras Included with ColorDome and LCD monitor Dimensions E 3 Console (WxDxH): 17 x 13 x 3.4 inches (432 x 330 x 86 mm) Computer (typ, 22 all-in-one): 21 x 14 x 2.5 inches (533 x 356 x 64 mm) Weight E 3 Console: 27 lbs (12.2 kg) Computer (typ, 22 all-in-one): 14 lbs (6.4 kg) E 3 system configurations Unique electrode lead testing system uses illuminated receptacles to guide lead insertion and indicate electrode contact quality, including ground Model number: D315 Configuration: select 1 option per field below Amplifier ote: all systems come with an E 3 console, 32-bit amplifier with stand, computer, Espion software and starter accessory kit. D Configuration 110 Volt ColorDome with Xenon (includes regular cable) with power supply, LCD display Colorburst Handheld Envoy Mini-OLED 1 family 1 power supply CDXSL desktop stand and chin rest 27 and chin rest 1 Stimulator with Stand on a table stand 220 Volt ColorDome with Xenon & desktop OR stand (includes long cable), with o LCD display Colorburst Handheld Stimulator with O 2 power supply CDXRL power supply, and chin rest or chin rest 2 Stand o Envoy ColorDome with O Xenon (includes regular cable) with power supply, CDSL desktop stand and chin rest o Colorburst Handheld Stimulator CDRL CDXFL CDFL ColorDome with O Xenon & desktop OR stand (includes long cable), with power supply, and chin rest ColorDome with Xenon & Floor Stand (includes long cable) ColorDome with O Xenon & Floor Stand (includes long cable) o ColorDome Optional accessories Model Description D343 Dark adaptation module (w/colordome) D196 Scotopic threshold module (w/colordome) D355 Pupillometry module (w/colordome) D CR US: Diagnosys LLC USA 55 echnology Dr, Suite 100 Lowell, MA USA Phone: Fax: sales@diagnosysllc.com UK: Diagnosys LD UK 5 rust Court, Vision Park Histon, Cambridge, CB24 9PW Phone/Fax: +44 (0) mail@diagnosysuk.co.uk he information listed herein is accurate as of the date of printing, however may change at any time without notice. he contents may differ from the current status of approval of the product in your country. Please contact your local Diagnosys representative for more information 2016 by Diagnosys, LLC. All copyrights reserved. Doc: #13601 Rev: #C EC 997 Date: 08/03/2017

6 Simplify your visual electrophysiology Diagnosys Lab [Espion: V ] 1 of 1 Patient: ORMAL, DOB:1/1/1950, Female Examine r : atalie Doran Date ested: 1/1/2012 (Updated: 11/16/2015) ime ested: 9:50:40 AM est Comment: Done w ith trial lenses Unique ID: B6E E8E-419E-BC71-01D6-05AA-BFA6 61 Hex 60 degree [11-Mar-2010] ormal patients will show a strong central peak and moderate peripheral responses in the surface plot. races should line up fairly well against normative data, and group averages should show markers within the normative data boxes. Patients with excellent fixation may even show a dip in function at the location of the blind spot. Group Averages Concentric Rings [RE] Group Averages Concentric Rings [LE] Response Density index Hex n Area deg² P1 ms P1 nv Response Density index Hex n Area deg² P1 ms P1 nv * * * * * * * * * * 3 50nV/deg² 3 50nV/deg² nV race Array races Average[3],Adaptive[3],Secondary Smoothed ormals [RE] Retinal () 500nV race Array races Average[3],Adaptive[3],Secondary Smoothed ormals [LE] Retinal () Espion software provides detailed test reports that are concise and easy to interpret nv/deg ² Patient 3-D opography RMS Density x ormals nv/deg² [RE] nv/deg² Patient 3-D opography RMS Density x ormals nv/deg² [LE] (ISCEV standard mferg tests using the E system with an LCD monitor shown). he industry leader. Decades of experience, thousands of installations. Most experienced customer support team in the industry Hundreds of peer-reviewed papers published using our systems Extensive world-wide network of leading experts operating Diagnosys systems Model #: System options: Ordering information: D315 ormative data (ERG and/or mferg) DICOM print module Dark adaptation module (w/red Profile) Scotopic threshold module (w/red Profile) Pupillometry module (w/red Profile) 19" CR high performance stimulator for ISCEV PERG and VEP If you would like more information on Diagnosys products, please contact us at either our US or UK locations. US: Diagnosys LLC USA 55 echnology Dr, Suite 100 Lowell, MA USA Phone: Fax: sales@diagnosysllc.com UK: Diagnosys LD UK 5 rust Court, Vision Park Histon, Cambridge, CB24 9PW Phone/Fax: +44 (0) mail@diagnosysuk.co.uk Doc #: Rev: C EC #: 997 Date: 08/03/2017

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