University of Groningen. The dark side of p-phenylenediamine Vogel, Tatiana Alexandra
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1 University of Groningen The dark side of p-phenylenediamine Vogel, Tatiana Alexandra IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2016 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Vogel, T. A. (2016). The dark side of p-phenylenediamine: Biological aspects and prevalence of contact allergy to an extraordinary molecule [Groningen]: Rijksuniversiteit Groningen Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:
2 The Dark Side of p-phenylenediamine Biological aspects and prevalence of contact allergy to an extraordinary molecule Tatiana Alexandra Vogel
3 The printing of this thesis was financially supported by: Department of Dermatology (UMCG), Fagron BV, Galderma BV, La Roche-Posay, LEO Pharma BV, University of Groningen, University Medical Center Groningen, Van der Bend, Will Pharma BV. The study in Chapter 6 was financially supported by the J.P. Nater Fund, the study in Chapter 7 was financially supported by the Stichting Milieu en Arbeidsdermatologie (SMAD). Layout Bianca Pijl, Groningen, The Netherlands Cover design Bianca Pijl, Photo on the cover Anke Vogel, Etching 8 of 15 (2005) Printed by Ipskamp Printing Enschede, The Netherlands ISBN (print) (digital) 2016 by Tatiana Alexandra Vogel No part of this book may be reproduced in any form without permission from the author.
4 The Dark Side of p-phenylenediamine Biological aspects and prevalence of contact allergy to an extraordinary molecule Proefschrift ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen op gezag van de rector magnificus, prof. dr. E. Sterken en volgens besluit van het College voor Promoties. De openbare verdediging zal plaatsvinden op maandag 14 maart 2016 om uur door Tatiana Alexandra Vogel geboren op 31 december 1983 te Gouda
5 Promotores Prof. dr. P. J. Coenraads Prof. dr. M. F. Jonkman Copromotor Dr. M. L. A. Schuttelaar Beoordelingscommissie Prof. dr. T. Rustemeyer Prof. dr. M. Fartasch Prof. dr. M. Bruze
6
7 Paranimfen: Wouter Bosma Eefje Spoorenberg
8 Contents Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Chapter 9 Appendices Introduction p-phenylenediamine exposure in real life A case-control study on sensitization rate, mode and elicitation reactions in the northern Netherlands ESSCA results with the baseline series, : p-phenylenediamine Two decades of p-phenylenediamine and 2,5-toluenediamine patch testing Focus on co-sensitizations in the European Baseline Series and cross-reactions with chemically related substances The attitude of patients with a p-phenylenediamine or 2,5-toluenediamine contact allergy towards hair dyeing The expression pattern of N-acetyltransferase 1 in healthy human skin The role of the antioxidant ascorbic acid on the elicitation of contact allergic reactions to p-phenylenediamine Allergic contact dermatitis presenting as severe and persistent blepharoconjunctivitis and centrofacialoedema after dyeing of eyelashes Discussion - List of abbreviations - Dutch summary/nederlandse samenvatting - List of publications - Acknowledgements/Dankwoord - About the author
9
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