ORDER FORM-Amendment AGREEMENT. Page 1 of 8 CLIENT DETAILS. Quote Date : December 18, 2018 REGENTS OF THE UNIVERSITY CALIFORNIA. Contracting Entity :

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ORDER FORM-Amendment Quote Date : December 18, 2018 Clarivate Analytics (US) LLC ("Clarivate") This Order Form is subject to the agreement and term referenced below, which outline the terms & conditions under which we will provide you the Products / Services described below. CLIENT DETAILS Contracting Entity : Client Address : REGENTS OF THE UNIVERSITY CALIFORNIA AGREEMENT Please refer to the Original Agreement entered between the parties dated January 1,1999 We agree to amend the Original Agreement as follows: To set forth the Fees for the Products/Services listed below for January 1, 2019 to December 31, 2019 Term. Except for the specific amendments set out in this Order Form, no other changes are agreed and the Original Agreement applies and shall remain in full force and effect. Page 1 of 8

PRODUCTS/SERVICES DETAILS Product(s) / Service(s) Level Rights Term Frequency of Payment FEES JOURNAL AND HIGHLY CITED DATA Annual WEB OF SCIENCE - BIOSIS PREVIEWS - WEB OF SCIENCE - BIOSIS CITATION INDEX - Annual WEB OF SCIENCE - CONFERENCE PROCEEDINGS CITATION INDEX - SOCIAL SCIENCE EDITION WEB OF SCIENCE - CONFERENCE PROCEEDINGS CITATION INDEX - SCIENCE & EDITION WEB OF SCIENCE - SCIENCE CITATION INDEX EXPANDED WEB OF SCIENCE - SOCIAL SCIENCES CITATION INDEX WEB OF SCIENCE - ARTS AND HUMANITIES CITATION INDEX Site (See Appendix A below) WEB OF SCIENCE - EMERGING SOURCES CITATION INDEX (ESCI) - Limited Annual WEB OF SCIENCE - INDEX CHEMICUS WEB OF SCIENCE - DERWENT INNOVATIONS INDEX WEB OF SCIENCE - CURRENT CHEMICAL REACTIONS WEB OF SCIENCE - BOOK CITATION INDEX SCIENCE & SOCIAL SCIENCE EDITION WEB OF SCIENCE - DATA CITATION INDEX Web of Science - MEDLINE Limited Limited Jan 1, 2019 - Dec 31, 2019 WEB OF SCIENCE - CURRENT CONTENTS CONNECT - CLINICAL MEDICINE - Limited Annual WEB OF SCIENCE - CURRENT CONTENTS CONNECT - AGRICULTURE BIOLOGY AND ENVIRONMENTAL SCIENCES - WEB OF SCIENCE - CURRENT CONTENTS CONNECT - ENGINEERING COMPUTING AND TECHNOLOGY WEB OF SCIENCE - CURRENT CONTENTS CONNECT - PHYSICAL CHEMICAL AND EARTH SCIENCES WEB OF SCIENCE - CURRENT CONTENTS CONNECT - SOCIAL AND BEHAVIORAL SCIENCES WEB OF SCIENCE - CURRENT CONTENTS CONNECT - ELECTRONICS AND TELECOMMUNICATIONS COLLECTION WEB OF SCIENCE - CURRENT CONTENTS CONNECT - LIFE SCIENCES - WEB OF SCIENCE - CURRENT CONTENTS CONNECT - BUSINESS COLLECTION - STANDARD WEB OF SCIENCE - CURRENT CONTENTS CONNECT - ARTS AND HUMANITIES - WEB OF SCIENCE - API - ARTICLE MATCH RETRIEVAL Limited Annual WEB OF SCIENCE - API LITE * (See Appendix A for list of Authorized Participating Members and Authorized Access to the Product/Databases.) Annual Annual Total Fee(s) US (See Exhibit A for Fee breakdow Page 2 of 8

*ADDITIONAL TERMS - API LICENSE Client may use our APIs to enable authorized users to use our products and services in accordance with the agreement in conjunction with your own technology systems provided Clarivate approved accreditations remain visible at all times. Our API keys must not be: (i) shared in any way; (ii) used for multiple interfaces; or (iii) used to create products or services detrimental to Clarivate, our affiliates or third party providers. Client must demonstrate interfaced systems if reasonably requested by Clarivate. **** Page 3 of 8

Clarivate Analytics Exhibit A UC Campus/COL Payment Resource Biosis Previews for UC Campus/COL* Biosis Previews for LLNL * Citation Connection Products Erner in Sources Citation Index ESCI Web of Science Sub INSPEC lncites JHCO / JCR Web Science Ed * * Web of Science*** Tota LLNL Payment Resource Biosis Previews (paid via campus)* Current Contents, 5 editions (Agriculture.., Clinical Med., En ineerin.., Life Sci., Ph sical Chemist r Emerging Sources Citation Index (ESCI) Web of Science Sub INSPEC lncites JHCO / JCR Web Science Ed * * Web of Science*** e f Scie ce Pr ceed'ngs ISTP To LBNL Payment Resource Biosis Previews* Emerging Sources Citation Index (ESCI) Web of Science Sub INSPEC lncites JHCO / JCR Web Science Ed*** Web of Science*** Web of Science Services Lite Article Match Retrieval Total NOTES: * Biosis Previews - LLNL portion is paid through campus/col. LBNL pays separately. * * lncites JHCO / JCR Web Sciende Ed. - each site pays separately. Page 4 of8

Clarivate Analytics * * * Web of Science - each site pays separately. This Amendment is subject to the terms and conditions set out in the Original Agreement as amended by the provisions of this Amendment (the "Terms and Conditions"). This Amendment is binding when countersigned by Client provided that Client has not made any changes to this Amendment. If Client modifies this Amendment, this Amendment shall be null and void. This Amendment is only valid if signed and returned to Clarivate on or before the date which is within ninety (90) days of Clarivate signature of the Amendment. Clarivate may, at its sole discretion, accept the Amendment if signed by Client after such date but is under no obligation to do so. If this Amendment is signed after the above-mentioned date, no legally binding agreement shall come into existence unless and until this Amendment is accepted by Clarivate. CLARIVATE ANALYTICS (US) LLC REGENTS OF THE UNIVERSITY OF CALIFORNIA TITLE: Vice President, Global Operations TITLE: Associate Executive Director DATE: December 19, 2018 DATE: 12/19/2018 Page 5 of 8

Clarivate Analytics Appendix A (Authorized Sites) PARTICIPATING MEMBER INSTITUTION University of California - Berkeley University of California - Davis University of California - San Francisco University of California - Irvine University of California - San Diego University of California - Santa Barbara University of California - Santa Cruz Page 6 of8 AUTHORIZED ACCESS TO DATABASE EDITIONS 1900-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1926-2019 BIOSIS Citation Index Archive (BCI) - lncites Journal and Highly Cited Data - 2015-2019 Emerging Sources Citation Index (ESCI) - Time Limited 1900-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data - 2015-2019 Emeraina Sources Citation Index /ESCI) - Time Limited 1965-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data- 2015-2019 Emeraina Sources Citation Index (ESCI) - Time Limited 1900-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data - Citation Connection Products.. 2015-2019 Emeraina Sources Citation Index (ESCI) - Time Limited 1900-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data - Citation Connection Products 2015-2019 Emeraina Sources Citation Index /ESCI) - Time Limited 1945-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data - Citation Connection Products.. 2015-2019 Emerging Sources Citation Index (ESCI) - Time Limited 1900-2019 Science Citation Index Expanded - 1900-2019 Social Sciences Citation Index - 1975-2019 Arts & Humanities Citation Index - 1926-1968 BIOSIS Citation Index Archive - 1969-2019 BIOSIS Citation Index - lncites Journal and Highly Cited Data - Citation Connection Product** 2015-2019 Emeraina Sources Citation Index /ESCI) - Time Limited

University of California Riverside University of California Los Angeles University of California Office of the President University of California Merced Lawrence Berkeley National Laboratory(LBNL) Lawrence Livermore National Laboratory (LLNL) 1900 2019 Science Citation Index Expanded 1900 2019 Social Sciences Citation Index 1975 2019 Arts & Humanities Citation Index 1926 1968 BIOSIS Citation Index Archive 1969 2019 BIOSIS Citation Index InCites Journal and Highly Cited Data - 1898 2019 INSPEC Time Limited 1900 2019 Science Citation Index Expanded 1900 2019 Social Sciences Citation Index 1975 2019 Arts & Humanities Citation Index 1926 1968 BIOSIS Citation Index Archive 1969 2019 BIOSIS Citation Index InCites Journal and Highly Cited Data - 1994 2019 Science Citation Index Expanded 1994 2019 Social Sciences Citation Index 1994 2019 Arts & Humanities Citation Index 1926 1968 BIOSIS Citation Index Archive 1969 2019 BIOSIS Citation Index 2010 & 2011 Journal Citation Reports-Science Edition Metrics File via Excel Science an Social Sciences editions InCites Journal and Highly Cited Data - 1900 2019 Science Citation Index Expanded 1900 2019 Social Sciences Citation Index 1975 2019 Arts & Humanities Citation Index 1926 1968 BIOSIS Citation Index Archive 1969 2019 BIOSIS Citation Index InCites Journal and Highly Cited Data - Citation Connection Products 1990-Current Conference Proceedings Citation Index (CPCI) - Science & Social Sciences & Humanities editions- 1900 2016 Science Citation Index Expanded 1926 1968 BIOSIS Previews Archive 1969 2016 BIOSIS Citation Index(upgrade from BIOSIS Previews) InCites Journal and Highly Cited Data Web of Science Services Lite Article Match Retrieval 2005 2016 Science Citation Index Expanded 1926 1968 BIOSIS Citation Index Archive 1969 2016 BIOSIS Citation Index 2001 2016 Conference Proceedings Citation Index(CPCI) Science & Technology Edition InCites Journal and Highly Cited Data - Current Contents Connect (CCC) Time Limited - Life Sciences - Clinical Medicine - Agriculture, Biology & Environmental Sciences - Engineering, Computing & Technology - Physical, Chemical & Earth Sciences Journal Citation Reports-Science Edition Metrics File via Excel 2010 & 2011 Journal Citation Reports-Science Edition Metrics File via Excel Science an Social Sciences editions 1963-2011 DII Database (One-Time Back Year) Page 7 of 8

**Citation Connection Package Products: 2005-2019 Book Citation Index (BKCI) - Science & Social Science Edition - 1990-2019 Conference Proceedings Citation Index (CPCI) - Science & Social Sciences edition- 1985-2019 Current Chemical Reactions (CCR) - 1900-2019 Data Citation Index (DCI) - Time Limited 1963-2019 Derwent Innovations Index (DII) - 1993-2019 Index Chemicus (IC) - 1950-2019 Medline - Time Limited Current Contents Connect (CCC) - Nine (9) Editions - Time Limited -Life Sciences (LS) -Clinical Medicine (CM) -Agriculture, Biology & Environmental Sciences (ABES) -Engineering, Computing & Technology (ECT) -Physical, Chemical & Earth Sciences (PCES) -Social & Behavioral Sciences (SBS) -Arts & Humanities (AH) -Electronic & Telecommunications Collection - Business Collection Page 8 of 8