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Title of Manuscript [97 characters max, including spaces] Alice B. Smith a, MD, Clarence Jones a,b, MD, PhD, Ann S. Noble b, MPH, Steve R. Eccleston b, MPH, William E. Piper a, PhD, Ellen Johnson, MSc, Murray Green, PhD, on behalf of Authoring Group (if any) Affiliations: a Children s Hospital, Chicago, Illinois; and b University of Chicago, Chicago, Illinois Address correspondence to: Alice Smith, Department of Pediatrics, Children s Hospital, 1234 Main Street, Chicago IL, 60641, [asmith@example.com], 773-900-9000. Short title: Short running title for Manuscript [55 characters maximum, including spaces] Funding Source: All phases of this study were supported by an NIH grant, ######. [or] No funding was secured for this study. Financial Disclosure: Clarence Jones has example disclosure. The remaining authors have no financial relationships relevant to this article to disclose. Conflict of Interest: Ann Noble has example conflict. Clarence Jones has other example conflict. The other authors have no conflicts of interest to disclose. Clinical Trial Registration (if any): Registry name, registration number, web link to study on registry, and data sharing statement Abbreviations: (list and define abbreviations used in the text; [or] Abbreviations: none) Table of Contents Summary Max 25 words; a brief insight into what the article is about; it should entice the reader to go beyond the table of contents page and read the full article.

Contributors Statement Page [Each author should only appear once. Use names, not initials. If multiple authors have identical contributions, list them in the same sentence; otherwise, list separately.] Dr Smith and Prof Jones conceptualized and designed the study, drafted the initial manuscript, and reviewed and revised the manuscript. Drs Noble, Eccleston, and Piper and Ms Johnson designed the data collection instruments, collected data, carried out the initial analyses, and reviewed and revised the manuscript. Dr Green conceptualized and designed the study, coordinated and supervised data collection, and critically reviewed the manuscript for important intellectual content. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Abstract [250 words max] This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is singlespaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced. This is an unstructured abstract. It is single-spaced.

[The Main Body Goes Here; State of the Art Review = 4,000 words max] This is my manuscript s main body. It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. 1 This is my manuscript s main body. It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. 2,3 This is my manuscript s main body. 4 It s in double-spaced, Times New Roman font, size 12. This is my manuscript s main body. It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. 5 This is my manuscript s main body. 6 It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. This is my manuscript s main body. 7 It s in double-spaced, Times New Roman font, size 12. 8 For a SOTA article, this section can be up to 4,000 words long. 9 For a SOTA article, this section can be up to 4,000 words long. This is my manuscript s main body. 10 It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. This is my manuscript s main body. 11 It s in double-spaced, Times New Roman font, size 12. For a SOTA article, this section can be up to 4,000 words long. 12 For a SOTA article, this section can be up to 4,000 words long.

Acknowledgements [Optional] Thank you to Dr. Jane Doe for her review of the manuscript. Thank you also to the research group at College University Medical Center for their contribution. References 1. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 2. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 3. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 4. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 5. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 6. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 7. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 8. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 9. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 10. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 11. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. 12. Smith A, Jones B, King G, et al. Article title goes here, 1900-2012. Pediatrics. Figure 1. This is the legend from a figure from the study. Figure 2. This is also a legend from a figure from the study. [Any figures or tables not appearing in this document may be uploaded through your Author Center. We cannot accept Excel (.xls,.xlsx) or Powerpoint (.ppt,.pptx) files.]