Optimized productivity through automation

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Capsule Filling and Closing Machine GKF 2500 ASB - GKF 2500 ASB IPK - GKF 2500 ASB 100% 1

Optimized productivity through automation The GKF 2500 series of machines with automatic troubleshooting system (ASB) ensures optimized productivity and pharmaceutical security for the filling of capsules. Versions GKF 2500 ASB, GKF 2500 ASB IPK or GKF 2500 ASB 100 %. 2

GKF 2500 ASB 100% with online weight control and optional tablet station The high degree of automation ensured by ASB provides for smooth production processing and ensures optimized productivity with minimum downtimes. The GKF 2500 ASB IPK with in-process control makes it possible for you to perform weight control by way of statistical evaluation with documentation of the random sample data, daily data and batch data. The GKF 2500 ASB 100 % is equipped with an integrated checkweigher. Each capsule is weighed individually and with high precision. Accepted are only those capsules of which the weight is within the preset tolerance limits. Any overweight or underweight capsules are rejected. 3

4 Easy operator control Optimized sealing technology Easy cleaning

Secure investment and production High-precision dosing for powder and pellets Wide range of dosing facilities, e.g. with optional tablet station Data security Consistently cgmp-compliant High-precision dosing Control and measured data acquisition design Proven dosing of powders on the tamp- are performed via an industrial PC. All The table top is made from one piece ing pin principle via the dosing disk. production data are stored and managed of material with no joints. With large Constant improvements have consid- here. The WINDOWS-based software chamfer radii and no undercuts. A erably enhanced the efficiency of the meets the requirements of 21 CFR part high-grade coating seals the surface system. Pellets and other non-tampable 11 for data security. smoothly and free from pores. Special products can be filled particularly gen- shaft seals separate the production tly via the dosing disk. The fill volume Easy operator control area from the drive area and prevent is adapted optimally to the amount of Operator control of the machine via foreign substances from getting into product by means of the height-adjust- touchscreen is very user-friendly. Posi- the product. able dosing disk. the user-friendly and easy-to-learn Low-maintenance operation Wide range of dosing facilities menu guidance via self-explanatory Encapsulated drive elements ensure The capsule is filled with other prod- symbols. that the lubricants cannot get into the ucts such as tablets, coated tablets tive points for the operating personnel: environment. The low-maintenance belt or pellets via additional, optional dos- Optimized accessibility drive provides for quiet running of the ing stations. Difficult products do not The production area is clearly and tidily machine, reduces wear and thus present a problem either. Make use of arranged. All stations are freely accessible thanks to the upward swiveling extends the entire service life. our experience. We shall be glad to give you our advice. guard doors. The ergonomic design of the machine and effortless disassembly of the stations contribute towards easy handling. This also means size-changing and cleaning without difficulty. 5 5

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Empty capsule feed and separation (stations 1 and 2) with mechanical capsule cap scanning (station 3) Individual capsule discharge (stations 10 and 11) Reliable production through ASB The automatic troubleshooting during production makes possible automated production and reduces downtimes. The calibration bar in the empty capsule magazine ensures that deformed or damaged empty capsules are already discharged before the filling process. The mechanical capsule cap scanning facility detects blockages in the capsule feed. The repeated occurrence of missing capsules in a segment bore is detected by the serial fault function. Any deformed capsules in the capsule magazine are blown out by means of a targeted pulse of compressed air and then collected in a bin. The capsule body scanning facility detects incomplete capsules during the closing process. No powder or capsule parts get into the production batch. Defective capsules are individually discharged via the 18 discharge flaps. The segment cleaning with blow nozzles reliably releases any adherent product and capsule remains from the segment borings and discharges these by means of suction air. This ensures thorough cleaning of the segments. 7

8

Automatic weight readjustment Precise weight determination by means of gravimetric weighing cells 9

Technical specifications GKF 2500 ASB GKF 2500 ASB IPK GKF 2500 ASB 100% Output: Machine cycles: Maximum 150,000 capsules/h Maximum 140 cycles/min. Number of segment bores: 18 Connected loads of the machine: Maximum series fuse: Connected load of the vacuum pump: Vacuum requirement: 400-440 V +/-10 %, 50 Hz, 400-460 V +/- 10 %, 60 Hz 3 ph/pe Non-standard voltages Connected loads in total 10 kva 1.85 kw, 50 Hz, 2.2 kw, 60 Hz 50 m 3 /h at -250 mbar 16A Compressed air requirement: 2 m 3 /h at 5 bar 4 m 3 /h at 5 bar 45 m 3 /h at 5 bar Connected load of the dust extractor: 400-440 V, 50 Hz, 4 kw, 400-440 V, 50 Hz, 8 kw, 400-460 V, 60 Hz, 4.6 kw 400-460 V, 60 Hz, 9.2 kw Suction air requirement: 7.2 m 3 /min 7.2 m 3 /min 12.9 m 3 /min Connections: Compressed air supply Ø13 mm Vacuum connection Ø30 mm Dust extractor connection 2x Ø70 mm Plug receptacle for vacuum pump Plug receptacle for jog cable Plug receptacle for dust extractor Main electrical connection Feeds: Powder feed triclamp DN 150 Pellet/tablet feed triclamp DN 100 Empty capsule feed triclamp DN 100 Weight: approx. 2000 kg approx. 2200 kg approx. 3300 kg Standard equipment: Sizes: Filling options: Accessories: Basic machine with integrated control cabinet and built-in control panel Machine control: industrial PC Empty capsule supply container with minimum and maximum level control Dosing station with fixed or height-adjustable dosing disk and product supply container Product supply container with minimum and maximum level control Adjusting device for reproducible adjustment of the dosing disk Capsule closing station with concave closing pins Cleaning station with plunging blow nozzles and extraction Capsule size set for all popular capsule sizes 00 to 5, DB Pellet station Tablet station for a wide range of tablet shapes Vacuum pump for capsule separation Dust extractor Automatic powder feed Empty capsule conveyor Capsule deduster Metal detector Container changer All right reserved to effect technical modifications. 10

Technical specifications GKF 2500 ASB 2762 1389 2762 1389 2343 2027 2027 2029 2466 2027 2029 2466 2220 GKF 2500 ASB IPK 2320 GKF 2500 ASB 100% 2762 2029 2466 3061 1389 11