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..... THE EGYPTIAN JOURNAL OF CRITICAL CARE MEDICINE Production and Hosting by Elsevier B.V. on behalf of the Egyptian College of Critical Care Physicians AUTHOR INFORMATION PACK TABLE OF CONTENTS XXX Description Abstracting and Indexing Editorial Board Guide for Authors p.1 p.1 p.1 p.3 ISSN: 2090-7303 DESCRIPTION The Egyptian Journal of Critical Care Medicine is the official Journal of the Egyptian College of Critical Care Physicians, the most authoritative organization of Egyptian physicians involved in the multi-professional field of critical care medicine. The journal is intended to provide a peer-reviewed source for multidisciplinary coverage of general acute and intensive care medicine and its various subcategories including cardiac, pulmonary, neuro, renal as well as post-operative care. The journal is proud to have an international multi-professional editorial board in the broad field of critical care that will assist in publishing promising research and breakthrough reports that lead to better patients care in life threatening conditions, and bring the reader a quick access to the latest diagnostic and therapeutic approaches in monitoring and management of critically ill patients. The Egyptian Journal of Critical Care Medicine is now indexed in the Emerging Science Citaion Index (ESCI). ABSTRACTING AND INDEXING Directory of Open Access Journals (DOAJ) EDITORIAL BOARD Editor-In-Chief Sherif Mokhtar, Professor of Cardiology and Critical Care Medicine; Founder and Former Director of Critical Care Center, Cairo University Hospitals, Cairo, Egypt; President of Egyptian College of Critical Care Physicians (ECCCP) Deputy Chief Editors Alia Abdel Fattah, Professor of Critical Care Medicine; Chairman of Critical Care Medicine Department, Cairo University Hospitals, Cairo, Egypt Tamer Fahmy, Associate Professor, Critical Care Medicine; Cardiac Electrophysiology Consultant, Critical Care Medicine Department, Cairo University Hospitals, Cairo, Egypt Editorial Board Medhat Abdel Khalek, Professor of Chest Medicine, Department of Chest Medicine, Cairo University Hospitals, Cairo, Egypt AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 1

Etienne Aliot, Cardiology Department, Nancy University Hospital, Barbois Hospital Nancy,Nancy, France Omar Awad, Professor of Cardiology, Department of Cardiology, Ain Shams University, Cairo, Egypt Ignasi Carrió, Professor of Nuclear Medicine, Autonomous University of Barcelona; Director, Nuclear Medicine Department, Hospital Sant Pau, Barcelona; Editor-in-Chief, Barcelona,Spain Antonio Curnis, Professor of Cardiology, Department of Cardiovascular Medicine, Section Head electrophysiology and pacing, Brescia, Italy Anthony N. DeMaria, Professor of Cardiovascular Medecine, Chair of Cardiology and Director of Cardiovascular Center, University of California in San Diego, San Diego, USA; Editor-in Chief, Journal of the American College of Cardiology. Antonio Matías Esquìnas, Hospital Morales Meseguer, Internsive Care Unit, Murcia, Spain Wagdi Galal, Professor of Cardiology, Department of Cardiology, Ain Shams University, Cairo, Egypt; President of the Egyptian Cardiac Rhythm Association. Mohamed Hammouda, Professor of Critical Care Medicine, Department of Critical Care Medicine ; Director of Critical Care Center, Cairo University Hospitals, Cairo, Egypt Hasan Hosny, Professor of Neurology and Neuro Critical Care, Cairo University Hospitals; Department of Neurology, Cairo University Hospitals, Cairo University, Cairo, Egypt Karl Isaaz, Professor of Cardiology, Cardiology Department, University of Saint Étienne, France Ami Iskandrian, Professor of Medicine and Radiology, Section Chief of Nuclear Cardiology, University of Alabama, Birmingham, USA John J. Marini, Professor of Pulmonary and Critical Care Medicine, University of Minnesota, Minnesota,USA Hosam Moafy, Professor of internal Medicine and Critical Care Medicine, Department of Critical Care Medicine, Cairo University Hospitals, Cairo, Egypt Claudio Muneretto, Professor of Cardiothoracic Surgery, Department of Cardiac Surgery, Brescia, Italy. Andrea Natale, Executive Medical Director, Texas Cardiac Arrhythmia Institute, St. David's Medical Center; Senior medical director of electrophysiology services, California Pacific Medical Center, San Francisco, USA. Marco Tubaro, Head of Intensive Cardiac Care Unit, Cardiovascular Department, San Filippo Neri Hospital, Rome, Italy. Jean-Louis Vincent, Head of Department of Intensive Care, Erasme Hospital, Free University of Brussels, Brussels, Belgium; editor-in-chief of Janice L Zimmerman, Professor of Clinical Medicine, Department of Medicine, Weill Cornell Medical College; Adjunct Professor of Medicine, Baylor College of Medicine; Head of the Critical Care Division, Department of Medicine; Director of the MICU, The Methodist Hospital, Houston, USA. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 2

. GUIDE FOR AUTHORS Submission checklist You can use this list to carry out a final check of your submission before you send it to the journal for review. Please check the relevant section in this Guide for Authors for more details. Ensure that the following items are present: One author has been designated as the corresponding author with contact details: E-mail address Full postal address All necessary files have been uploaded: Manuscript: Include keywords All figures (include relevant captions) All tables (including titles, description, footnotes) Ensure all figure and table citations in the text match the files provided Indicate clearly if color should be used for any figures in print Graphical Abstracts / Highlights files (where applicable) Supplemental files (where applicable) Further considerations Manuscript has been 'spell checked' and 'grammar checked' All references mentioned in the Reference List are cited in the text, and vice versa Permission has been obtained for use of copyrighted material from other sources (including the Internet) A competing interests statement is provided, even if the authors have no competing interests to declare Journal policies detailed in this guide have been reviewed Referee suggestions and contact details provided, based on journal requirements For further information, visit our Support Center. BEFORE YOU BEGIN Ethics in publishing Please see our information pages on Ethics in publishing and Ethical guidelines for journal publication. Policy and ethics The work described in your article must have been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans http://www.wma.net/en/30publications/10policies/b3/index.html; EU Directive 2010/63/EU for animal experiments http://ec.europa.eu/environment/chemicals/lab_animals/legislation_en.htm; Uniform Requirements for manuscripts submitted to Biomedical journals http://www.icmje.org. This must be stated at an appropriate point in the article. The authors should also state that the study protocol has been approved by the Institutional review board. Conflict of interest All authors must disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/ registrations, and grants or other funding. See also http://www.elsevier.com/conflictsofinterest. Please complete and upload the Conflict of Interest and Author Declaration form with your manuscript. Inclusion of this form is mandatory. Submission declaration and verification Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see 'Multiple, redundant or concurrent publication' section of our ethics policy for more information), AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 3

that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection service Crossref Similarity Check. Contributions and authorship Each author is required to declare his or her individual contribution to the article: all authors must have materially participated in the research and/or article preparation, so roles for all authors should be described. The statement that all authors have approved the final article should be true and included in the disclosure. The contribution of each must be substantiated in the cover letter. All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted. A signed approval by all authors of the final submitted version of the manuscript with their substantial role of each author should be scanned and sent with additional material. (esignatures are also acceptable). Changes to authorship Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed. Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum. Clinical trial results In line with the position of the International Committee of Medical Journal Editors, the journal will not consider results posted in the same clinical trials registry in which primary registration resides to be prior publication if the results posted are presented in the form of a brief structured (less than 500 words) abstract or table. However, divulging results in other circumstances (e.g., investors' meetings) is discouraged and may jeopardise consideration of the manuscript. Authors should fully disclose all posting in registries of results of the same or closely related work. Reporting clinical trials Randomized controlled trials should be presented according to the CONSORT guidelines. At manuscript submission, authors must provide the CONSORT checklist accompanied by a flow diagram that illustrates the progress of patients through the trial, including recruitment, enrollment, randomization, withdrawal and completion, and a detailed description of the randomization procedure. The CONSORT checklist and template flow diagram are available online. Registration of clinical trials Registration in a public trials registry is a condition for publication of clinical trials in this journal in accordance with International Committee of Medical Journal Editors recommendations. Trials must register at or before the onset of patient enrolment. The clinical trial registration number should be included at the end of the abstract of the article. A clinical trial is defined as any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects of health outcomes. Health-related interventions include any intervention used to modify a biomedical or health-related outcome (for example drugs, surgical procedures, devices, behavioural treatments, dietary interventions, and process-of-care changes). Health outcomes include any biomedical or health-related measures obtained in patients or participants, including pharmacokinetic measures and adverse events. Purely observational studies (those in which the assignment of the medical intervention is not at the discretion of the investigator) will not require registration. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 4

Copyright Upon acceptance of an article, authors will be asked to complete an 'Exclusive License Agreement' (see more information on this). Permitted third party reuse of open access articles is determined by the author's choice of user license. Author rights As an author you (or your employer or institution) have certain rights to reuse your work. More information. Elsevier supports responsible sharing Find out how you can share your research published in Elsevier journals. Role of the funding source You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated. Open access Every peer-reviewed research article appearing in this journal will be published open access. This means that the article is universally and freely accessible via the internet in perpetuity, in an easily readable format immediately after publication. The author does not have any publication charges for open access. The Egyptian College of Critical Care Physicians will pay to make the article open access. A CC user license manages the reuse of the article (see http://www.elsevier.com/openaccesslicenses). All articles will be published under the following license: Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) For non-commercial purposes, lets others distribute and copy the article, and to include in a collective work (such as an anthology), as long as they credit the author(s) and provided they do not alter or modify the article. Elsevier Publishing Campus The Elsevier Publishing Campus (www.publishingcampus.com) is an online platform offering free lectures, interactive training and professional advice to support you in publishing your research. The College of Skills training offers modules on how to prepare, write and structure your article and explains how editors will look at your paper when it is submitted for publication. Use these resources, and more, to ensure that your submission will be the best that you can make it. Language (usage and editing services) Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop. Informed consent and patient details Studies on patients or volunteers require ethics committee approval and informed consent, which should be documented in the paper. Appropriate consents, permissions and releases must be obtained where an author wishes to include case details or other personal information or images of patients and any other individuals in an Elsevier publication. Written consents must be retained by the author and copies of the consents or evidence that such consents have been obtained must be provided to Elsevier on request. For more information, please review the Elsevier Policy on the Use of Images or Personal Information of Patients or other Individuals. Unless you have written permission from the patient (or, where applicable, the next of kin), the personal details of any patient included in any part of the article and in any supplementary materials (including all illustrations and videos) must be removed before submission. Submission Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 5

Referees Please submit the names and institutional e-mail addresses of several potential referees. For more details, visit our Support site. Note that the editor retains the sole right to decide whether or not the suggested reviewers are used. PREPARATION Peer review This journal operates a double blind review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. More information on types of peer review. Use of word processing software It is important that the file be saved in the native format of the word processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. In particular, do not use the word processor's options to justify text or to hyphenate words. However, do use bold face, italics, subscripts, superscripts etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row. If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier). Note that source files of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on Electronic artwork. To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor. Article Guide The article should not exceed 5000 words. The text must be single columned, and double-spaced. The manuscript should be arranged as follows: 1) title page; 2) structured abstract and key words; 3) abbreviations list; 4) text; 5) acknowledgments (if applicable); 6) references; 7) figure titles and legends; and 8) tables. Page numbering should begin with the title page. Essential title page information Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible. Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author. Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that phone numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address. Contact details must be kept up to date by the corresponding author. Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes. Abstract A concise and factual abstract is required. Abstracts should not exceed 250 words. The abstract should state briefly the purpose of the research, the principal results and major conclusions. An abstract is often presented separately from the article, so it must be able to stand alone. For this reason, References should be avoided, but if essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 6

Keywords Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes. Abbreviations Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article. Journal abbreviations source Journal names should be abbreviated according to: List of title word abbreviations: http://www.issn.org/2-22661-ltwa-online.php; NLM Catalog (Journals referenced in the NCBI Databases): http://www.ncbi.nlm.nih.gov/nlmcatalog/journals; CAS (Chemical Abstracts Service): via http://www.cas.org/content/references/corejournals. Main text The text should be structured as Introduction, Methods, Results, and Discussion. Use headings and subheadings in the Methods, Results, and, particularly, Discussion sections. Subdivision - numbered sections Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1 (then 1.1.1, 1.1.2,...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for internal cross-referencing: do not just refer to 'the text'. Any subsection may be given a brief heading. Each heading should appear on its own separate line. Introduction State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results. Theory/calculation A Theory section should extend, not repeat, the background to the article already dealt with in the Introduction and lay the foundation for further work. In contrast, a Calculation section represents a practical development from a theoretical basis. Material and methods Provide sufficient detail to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described. Statistical methods: In the Methods section, authors should provide a subsection detailing the statistical methods used, including specific methods used to summarize the data, methods used for hypothesis testing (if any), and the level of significance used for hypothesis testing. When using more sophisticated statistical methods (beyond t tests, chi-square, simple linear regression), specify the statistical package, version number, and non-default options used. Results Results should be clear and concise. The results should be presented either in the text, the figures, or the tables and should not be repeated. the results should be clearly presented, but the interpretation should only be mentioned in the discussion Discussion This should explore the significance of the results of the work, not repeat them. A separate section on Clinical implications is generally preferred but is mandatory in experimental studies. Avoid extensive citations and discussion of published literature. Conclusions The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 7

Footnotes Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript Arabic numbers. Many wordprocessors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at the end of the article. Do not include footnotes in the Reference list. Table footnotes Indicate each footnote in a table with a superscript lowercase letter. Appendices If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on. Similarly for tables and figures: Table A.1; Fig. A.1, etc. Acknowledgements Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing assistance or proof reading the article, etc.). Formatting of funding sources List funding sources in this standard way to facilitate compliance to funder's requirements: Funding: This work was supported by the National Institutes of Health [grant numbers xxxx, yyyy]; the Bill & Melinda Gates Foundation, Seattle, WA [grant number zzzz]; and the United States Institutes of Peace [grant number aaaa]. It is not necessary to include detailed descriptions on the program or type of grants and awards. When funding is from a block grant or other resources available to a university, college, or other research institution, submit the name of the institute or organization that provided the funding. If no funding has been provided for the research, please include the following sentence: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Artwork Image manipulation Whilst it is accepted that authors sometimes need to manipulate images for clarity, manipulation for purposes of deception or fraud will be seen as scientific ethical abuse and will be dealt with accordingly. For graphical images, this journal is applying the following policy: no specific feature within an image may be enhanced, obscured, moved, removed, or introduced. Adjustments of brightness, contrast, or color balance are acceptable if and as long as they do not obscure or eliminate any information present in the original. Nonlinear adjustments (e.g. changes to gamma settings) must be disclosed in the figure legend. Electronic artwork General points Make sure you use uniform lettering and sizing of your original artwork. Embed the used fonts if the application provides that option. Aim to use the following fonts in your illustrations: Arial, Courier, Times New Roman, Symbol, or use fonts that look similar. Number the illustrations according to their sequence in the text. Use a logical naming convention for your artwork files. Provide captions to illustrations separately. Size the illustrations close to the desired dimensions of the published version. Submit each illustration as a separate file. A detailed guide on electronic artwork is available. You are urged to visit this site; some excerpts from the detailed information are given here. Formats If your electronic artwork is created in a Microsoft Office application (Word, PowerPoint, Excel) then please supply 'as is' in the native document format. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 8

Regardless of the application used other than Microsoft Office, when your electronic artwork is finalized, please 'Save as' or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below): EPS (or PDF): Vector drawings, embed all used fonts. TIFF (or JPEG): Color or grayscale photographs (halftones), keep to a minimum of 300 dpi. TIFF (or JPEG): Bitmapped (pure black & white pixels) line drawings, keep to a minimum of 1000 dpi. TIFF (or JPEG): Combinations bitmapped line/half-tone (color or grayscale), keep to a minimum of 500 dpi. Please do not: Supply files that are optimized for screen use (e.g., GIF, BMP, PICT, WPG); these typically have a low number of pixels and limited set of colors; Supply files that are too low in resolution; Submit graphics that are disproportionately large for the content. Figure captions Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used. Tables Please submit tables as editable text and not as images. Tables can be placed either next to the relevant text in the article, or on separate page(s) at the end. Number tables consecutively in accordance with their appearance in the text and place any table notes below the table body. Be sparing in the use of tables and ensure that the data presented in them do not duplicate results described elsewhere in the article. Please avoid using vertical rules and shading in table cells. Reference management software Most Elsevier journals have their reference template available in many of the most popular reference management software products. These include all products that support Citation Style Language styles, such as Mendeley and Zotero, as well as EndNote. Using the word processor plug-ins from these products, authors only need to select the appropriate journal template when preparing their article, after which citations and bibliographies will be automatically formatted in the journal's style. If no template is yet available for this journal, please follow the format of the sample references and citations as shown in this Guide. Users of Mendeley Desktop can easily install the reference style for this journal by clicking the following link: http://open.mendeley.com/use-citation-style/the-egyptian-journal-of-critical-care-medicine When preparing your manuscript, you will then be able to select this style using the Mendeley plugins for Microsoft Word or LibreOffice. Supplementary material Supplementary material such as applications, images and sound clips, can be published with your article to enhance it. Submitted supplementary items are published exactly as they are received (Excel or PowerPoint files will appear as such online). Please submit your material together with the article and supply a concise, descriptive caption for each supplementary file. If you wish to make changes to supplementary material during any stage of the process, please make sure to provide an updated file. Do not annotate any corrections on a previous version. Please switch off the 'Track Changes' option in Microsoft Office files as these will appear in the published version. Other paper categories The following information should be noted for these paper types: Literature/Systematic Review Articles: Such manuscripts must adhere to preferred length guidelines and require an unstructured abstract of no more than 250 words. Authors should detail in their cover letters how their submission differs from existing reviews on the subject. Editorials and Viewpoints : Succinct opinion pieces will also be considered. These papers should have a brief unstructured abstract. Editorial Comments: The editors invite all Editorial Comments published in the Journal. AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 9

Letters to the Editor: A limited number of letters will be published. They should not exceed 500 words and should focus on a specific article that has appeared in EJCCM. Letters must be submitted within 3 weeks of the print issue date of the article. No original data may be included. Letters should also be double-spaced and include the cited article as a reference. Provide a title page that includes authors' names and institutional affiliations and a complete address for correspondence. Case Report: Case reports should be approximately 1000 to 2000 words. They must include a structured abstract. The number of references, tables, and figures should be appropriate for the overall length of the paper. In general, no more than 2 tables or 2 figures are necessary. Article submission Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail. Furthermore, the manuscripts must be submitted with a cover letter which states the following: 1) the paper is not under consideration elsewhere; 2) none of the paper's contents have been previously published; 3) all authors have read and approved the manuscript; and 4) the full disclosure of any relationship with industry (see "Relationship with Industry Policy"). Also,the corresponding author should be specified in the cover letter, and the roles of the different authors should be mentioned in this section. It is also important to include a short paragraph telling the editors why the authors think their paper merits publication priority may be included in the cover letter. Potential reviewers may be suggested in the cover letter, as well as reviewers to avoid. Submit your article Please submit your article via :http://ees.elsevier.com/ejccm/ AFTER ACCEPTANCE Online proof correction Corresponding authors will receive an e-mail with a link to our online proofing system, allowing annotation and correction of proofs online. The environment is similar to MS Word: in addition to editing text, you can also comment on figures/tables and answer questions from the Copy Editor. Web-based proofing provides a faster and less error-prone process by allowing you to directly type your corrections, eliminating the potential introduction of errors. If preferred, you can still choose to annotate and upload your edits on the PDF version. All instructions for proofing will be given in the e-mail we send to authors, including alternative methods to the online version and PDF. We will do everything possible to get your article published quickly and accurately. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. It is important to ensure that all corrections are sent back to us in one communication. Please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proofreading is solely your responsibility. Author Inquiries Track your submitted article Track your accepted article Contact Deputy Chief Editor tamfahmy@gmail.com. You are also welcome to contact the Elsevier Contact Center. Copyright 2018 Elsevier https://www.elsevier.com AUTHOR INFORMATION PACK 2 Jan 2018 www.elsevier.com/locate/ejccm 10