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Agilent Site Preparation 1260 Infinity Checklist Purification Solution Thank you for purchasing Agilent 1260 Infinity Purification Solution. To get you started and to assure a successful and timely installation, please refer to this specification or set of requirements. Correct site preparation is the key first step in ensuring that your instruments and software systems operate reliably over an extended lifetime. This document is an information guide AND checklist prepared for you that outlines the supplies, consumables, space and utility requirements for your equipment. Customer Responsibilities Make sure your site meets the following prior to the installation date using the checklist below. For details, see specific sections within this document, including: The necessary laboratory or bench space is available. The environmental conditions for the lab as well as laboratory gases, tubing. The power requirements related to the product (e.g. number & location of electrical outlets). The required operating supplies necessary for the product and installation. Please consult Other/Special Requirements section below for other product-specific information. If Agilent is delivering installation and familiarization services, users of the instrument should be present throughout these services; otherwise, they will miss important operational, maintenance and safety information. Important Customer Information If you have questions or problems in providing anything described as Customer Responsibilities above, please contact your local Agilent or partner support/service organization for assistance prior to delivery. In addition, Agilent and/or its partners reserve the right to reschedule the installation dependent upon the readiness of your laboratory. Should your site not be ready for whatever reasons, please contact Agilent as soon as possible to re-arrange any services that have been purchased. Other optional services such as additional training and consultation for user-specific applications may also be provided at the time of installation when ordered with the system, but should be contracted separately. If applicable, the Network Assessment Tool can be used to verify the network environment. Page 1 of 11

Module List Module G1170A G1310B G1311B G1315C G1315D G1364B G1365C G1365D G1390B G1968F G6120B G6130B G7110B G7111B G7114A G7115A G7159B G7165A Instrument Description 1290 Infinity Valve Drive and Valve Heads 1260 Infinity Isocratic Pump 1260 Infinity Quaternary Pump 1260 Infinity Diode Array Detector VL+ 1260 Infinity Diode Array Detector VL 1260 Infinity Preparative Pump 1260 Infinity Preperative-scale Fraction Collector 1260 Infinity Multiple Wavelength Detector 1260 Infinity Multiple Wavelength Detector VL 1200 Infinity Series Universal Interface Box 1260 Preparative Pump Gradient Extension Active Splitter 1260 Infinity Dual-Loop Autosampler Agilent 6120 Single Quadrupole LC/MS Agilent 6130 Single Quadrupole LC/MS 1260 Infinity II Isocratic Pump 1260 Infinity II Quaternary Pump 1260 Infinity II Variable Wavelength Detector 1260 Infinity II Diode Array Detector 1290 Infinity II Preparative Open-Bed Fraction Collector 1260 Infinity II Multiple Wavelength Detector Page 2 of 11

Dimensions and Weight Identify the laboratory bench space before your system arrives based on the table below. Pay special attention to the total height and total weight requirements for all system components you have ordered and avoid bench space with overhanging shelves. Also pay special attention to the total weight of the modules you have ordered to ensure your laboratory bench can support this weight. Table 1 Module Dimension and Weight Specifications - for Agilent 1260 Infinity Purification Solution Specification (height width depth) Weight G1310A 180 345 435 mm 11 kg / 200 345 440 mm 15 kg 200 345 440 mm 14 kg G1315C 140 x 345 x 435 mm 11.5 kg G1364B 200 345 440 mm 13.5 kg G6120B/G6130B 1 (including foreline pump 2 ) 1 For more details, refer to the 6100 Series Single Quad LCMS Site Preparation Guide. 2 Foreline pump requires extra space below the bench 575 730 690 mm approximately 100 kg G7110B/G7111B 180 x 396 x 436 14 kg G7114A 140 x 396 x 436 mm 11 kg G7115A/ G7165A 140 x 396 x 436 mm 12 kg G7159B 781 x 393 x 622 mm 30.6 kg Page 3 of 11

Environmental Conditions Operating your instrument within the recommended temperature ranges ensures optimum instrument performance and lifetime. Special Notes 1 Performance can be affected by sources of heat and cold, e.g. direct sunlight, heating/cooling from air conditioning outlets, drafts and/or vibrations. 2 The site s ambient temperature conditions must be stable for optimum performance. 3 The following table summarizes some key physical specifications. For the complete set of physical specifications, please refer to the corresponding module manual. Instrument Description G1315C/D, G1365C/D, G1364B, Operating temp range C (F) Operating humidity range (%) 0 55 C (32 131 F), constant temperature. < 95 %, non-condensing 4 40 C (39 104 F) < 95 %, non-condensing G1968F 0 40 C (32 104 F), constant temperature 80 % r.h. up to 31 C, decreasing to 50 % at 40 C, non-condensing G6120B, G6130B 1 15 35 C (59 95 F), constant temperature < ±3 C from the calibration temperature < 80 % r. h. G7110B/G7111B 4 55 C (39 131 F) < 95 % r.h. at 40 C40 C (104 F), non-condensing G7114A 4 55 C (39 131 F) < 95 % r.h. at 40 C40 C (104 F), non-condensing G7115A/ G7165A 4 55 C (39 131 F) < 95 % r.h. at 40 C40 C (104 F), non-condensing G7159B 4 40 C (39 104 F)? 80 % r.h. up to 31 C, decreasing to 50 % r.h. at 40 C, non-condensing All other modules 4 55 C (39 131 F), constant temperature < 95 % r.h. at 40 C, non-condensing 1 For more details, refer to the 6100 Series Single Quad LCMS Site Preparation Guide Page 4 of 11

Power Consumption Special Notes: 1 If a computer system is supplied with your instrument, be sure to account for those electrical outlets. 2 The heat dissipation can be calculated from the active power, using the following equation: 1 W = 3.413 BTU/h Instrument Description Line Voltage & Frequency (V, Hz) Maximum Power Consumption (VA) Maximum Power Consumption (W) G1310B 100 240 V(AC), 50 or 60 Hz 180 VA 55 W 100 240 V(AC), 50 or 60 Hz 250 VA 210 W 100 240 V(AC), 50 or 60 Hz 260 VA 210 W G1364B 100 240 V(AC), 50 or 60 Hz 200 VA 180 W G1315C/D, G1365C/D 100 240 V(AC), 50 or 60 Hz 160 VA 160 W G1390B 100 240 V(AC), 50 or 60 Hz 140 VA 65 W G1968F 100 240 V(AC), 50 or 60 Hz 93 111 VA N/A G6120B/G6130B 1 200 240 V(AC), 50 or 60 Hz 2000 VA 2000 W G7110B/G7111B 100 250 V(AC) ± 10 %, 50 or 60 Hz, ± 5 % 80 VA 65 W G7114A 100 250 V(AC) ± 10 %, 50 or 60 Hz, ± 5 % 80 VA 70 W G7115A/ G7165A 100 250 V(AC) ± 10 %, 50 or 60 Hz, ± 5 % 110 VA 100 W G7159B 100 250 V(AC) ± 10 %, 50 or 60 Hz, ± 5 % 350 VA 350 W 1 For more details, refer to the 6100 Series Single Quad LCMS Site Preparation Guide Page 5 of 11

Required Operating Supplies by Customer Special Notes: For information on Agilent consumables, accessories and laboratory operating supplies, please visit http://www.chem.agilent.com/en-us/products/consumables/pages/default.aspx Page 6 of 11

Other/Special Requirements G6120B/G6130B For details, refer to the 6100 Series Single Quad LCMS Site Preparation Guide. It is suggested that the MSD runs of a UPS to allow for a proper shut down which extends the life of the MSD. This can be a site-wide UPS or a standalone UPS. If standalone, it will need to allow for 3000 6000 VA. Page 7 of 11

Stack Configurations NOTE Clustering of the Open-Bed Fraction Collector is not yet supported in the drivers. G1170A G7159B G7111B G6120 or G6130 G7115A Figure 1 Stack configuration for 1260 Infinity combined analytical and preparative system with UV- and MS-Detection (example configuration with the 1290 Infinity II Preparative Open-Bed Fraction Collector) 2 x G1170A G7111B 3 x G1364B G7114A Figure 2 G6120 or G6130 Stack configuration for 1260 Infinity combined analytical and preparative system with UV- and MS-Detection (example shows configuration with 3 FCs in a clustered configuration - optionally available to be stacked in the same order with one FC and only one valve and one valve drive) Page 8 of 11

G7159B G7110B G6120 or G6130 G7115A Figure 3 Stack configuration for 1260 Infinity Purification System with UV- and MS-Detection (example configuration with the 1290 Infinity II Preparative Open-Bed Fraction Collector) G1170A G7110B 3 x G1364B G6120 or G6130 G7114A Figure 4 Stack configuration for 1260 Infinity Purification System with UV- and MS-Detection (example shows configuration with 3 FCs in a clustered configuration - optionally available to be stacked in the same order with one FC and only one valve and one valve drive) Page 9 of 11

G7159B G7114A Figure 5 Stack configuration for 1260 Infinity, preparative system with UV-Detection and Open-Bed Fraction Collector G1170A 3 x G1364B G7114A Figure 6 Stack configuration for 1260 Infinity, preparative system with UV-Detection (example shows option with 3 FCs in a clustered configuration - optionally available to be stacked in the same order with one FC and only one valve and one valve drive) Page 10 of 11

Document Control Logs Table 2 Revision Log Revision Date Reason For Update 1.0 12-Mar-2014 Initial Revision 1.1 20-Mar-2015 Added modules G1311B, G1365C/D, G1383A; Minor corrections 1.2 25-Nov-2016 New stack configurations Table 3 Approval Log Revision Approver Title of Approver 1.0 NN NN 1.1 Petro van Poppel Support Engineer 1.2 Stefan Ullrich Product Manager Page 11 of 11