Part III: How to Present in the Health Sciences

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CONTENTS Preface Foreword xvii xix 1. An Overview of Writing and Publishing in the Health Sciences 1 Part I: How to Write in the Health Sciences 2. How to Write Effectively: Making Reading Easier 29 3. How to Write Efficiently: Making Writing Easier 50 4. How to Display Data in Tables and Graphs 67 5. How to Write an Abstract 101 6. How to Write a Grant Proposal 118 7. How to Write a Journal Article Reporting Original Research 139 Part II: How to Publish in the Health Sciences 8. Ethics in Research and Publishing 177 9. How to Prepare Drawings and Photographs for Publication 206 10. How to Document Biomedical Images for Publication 229 11. How to Publish in a Scientific Journal 261 Part III: How to Present in the Health Sciences 12. How to Prepare and Present a Scientific Poster 289 13. How to Prepare and Present Slides 313 Appendix: The Value of Systematic Reviews as Research Activities in Medical Education 349 Index 361 About the Author 387

EXPANDED CONTENTS 1. An Overview of Writing and Publishing in the Health Sciences 1 A Brief History of Scientific Publications 2 The First Scientific Journals 2 The Development of the Scientific Article 4 The Beginnings of Organized Biomedical Writing and Publishing 6 Advances in Scientific Reporting and Documentation 10 Types of Scientific Articles 13 Observational Articles 13 Theoretical Articles 15 Experimental Articles 15 Methodological Articles 16 Review Articles 16 Other Forms of Communication in Journals 17 Types of Journals 17 Electronic Publications 18 Online Journals 18 Preprint Servers 20 Open-Access Publishing 20 Self-Archiving 21 Books 21 The Future 23 Part I: How to Write in the Health Sciences 27 2. How to Write Effectively: Making Reading Easier 29 Moving from Practice Writing to Applied Writing 30 Qualities of Effective Writing 32 Attending to Your Readers 34 Attending to Your Subject 35 How to Make Your Writing Effective 37 Use Effective Words 37 Construct Effective Sentences 40 Write Effective Paragraphs 45 Subdivide the Text Purposefully 46 A Note about Readability Formulas 47 3. How to Write Efficiently: Making Writing Easier 50 Preparing to Write 51 The Process of Writing 51 Stage 1: Planning the Text 52 Stage 2: Drafting the Text 60

xi Stage 3: Revising the Text 61 Stage 4: Polishing the Text 63 Collaborative Writing 65 4. How to Display Data in Tables and Graphs 67 Common Components of Tables and Graphs 68 Choosing between Tabular and Graphic Displays 69 What Level of Detail Do You Want to Show? 69 Do You Want to Help Readers Analyze or Reference Information? 71 Do You Want to Show Exact Values or Patterns in the Values? 74 General Principles for Displaying Data 77 Tables and How to Design Them 80 Parts of a Table 80 Principles of Table Design 81 Graphs and How to Design Them 86 Types of Graphs 87 Parts of a Graph 90 Principles of Graph Design 91 Specific Applications of Tables and Graphs 95 5. How to Write an Abstract 101 The Purpose of Abstracts 102 The Problems of Abstracts 103 Publication Abstracts 105 Meeting Abstracts 107 Steps in Writing Abstracts 111 Ways to Reduce Word Counts 111 6. How to Write a Grant Proposal 118 An Overview of the Grant Proposal Process 119 Funding Agencies 120 Grants and Contracts Offices 121 Types of Grant Proposals 122 Research Grant Proposals 122 Service Delivery Proposals 123 Grants to Individuals 123 Developing a Grant Proposal 124 Evaluating Your Idea 124 Writing a Concept Paper 125 Finding a Potential Funding Source 125 How to Read Guidelines and Program Announcements 126 Writing the Proposal 127

xii Preparing the Budget 131 Submitting the Proposal 132 Characteristics of Successful and Unsuccessful Proposals 133 Industry-Sponsored Research 136 7. How to Write a Journal Article Reporting Original Research 139 Getting Oriented 140 Preparing the Title Page 141 Writing the Title 143 Writing the Abstract 147 Key Words and Abbreviations 148 Writing the Introduction 148 Writing the Methods Section 150 General Information on Experimental Methods 151 General Information on Measurements 152 General Information on Statistical Methods 154 Features of Basic Research Articles 155 Features of Clinical Research Articles 157 Writing the Results Section 158 Supplemental Data 160 Writing the Discussion Section 161 Writing the Acknowledgments 163 Citing and Organizing References 163 What Should Be Referenced 163 Where to Place Reference Citations 164 How to Prepare the Reference List 164 Reference Management Software 167 Organizing Tables and Figures 168 Tables 169 Charts, Graphs, Drawings, and Illustrations 169 Photographs 170 Clinical and Laboratory Images 170 Presenting Equations 170 Part II: How to Publish in the Health Sciences 175 8. Ethics in Research and Publishing 177 Ethics in Conducting Research 177 Protecting Human Subjects 177 Assuring Patient Privacy 178 Protecting Animal Subjects 180

xiii Registering Clinical Trials 181 Making Research Results Publicly Available 183 Scientific Misconduct 184 Fabricating Data 185 Falsifying Data 186 Fraud 186 Ethics in Writing 187 Authorship 187 Variations of Authorship 188 Plagiarism and Copyright Violations 191 Ethics in Publishing 193 Suppressing Research Findings 193 Duplicate and Redundant Publication 193 Divided Publication: Salami Science 196 Confidentiality of Editors and Reviewers 197 Conflicts of Interests 197 Ethical Gray Areas: Framing and Spinning 200 9. How to Prepare Drawings and Photographs for Publication 206 Planning Drawings and Photographs 207 Types and Functions of Images 207 Subjects and Backgrounds of Images 208 Contrast between Subject and Background 209 Image Resolution 210 Image Size 212 Image Captions 213 Preparing Drawings: Line Art 213 Preparing Photographs and Continuous-Tone Art 214 Submitting Digital Images for Publication 216 Graphic Formats 218 Color Models 220 Color Depth 222 File Naming Conventions 223 Image Compression 224 Image Manipulation 224 Submitting Print Images for Publication 225 Submitting Audio and Video Clips 227 10. How to Document Biomedical Images for Publication 229 Components of Image Documentation 230 Image Enhancement and Modification 231

xiv Implications of Diagnostic Images 232 Characteristics of Clinical Images 233 Characteristics of the Subject 234 Characteristics of Image Acquisition 234 Characteristics of the Image 235 Interpretation of the Image 235 Guidelines for Documenting Clinical Images 236 Clinical Photographs 236 Plain Radiographs 238 Fluoroscopic Images 240 Sonograms 241 CAT Scans 242 MRI Scans 243 Radionuclide Images 245 Electrocardiograms 247 Electroencephalograms 248 Characteristics of Laboratory Images 251 Characteristics of the Subject 251 Characteristics of Image Acquisition 252 Characteristics of the Image 252 Interpretation of the Image 252 Guidelines for Documenting Laboratory Images 253 Micrographs 253 Gels and Blots 255 Genetic Sequence Information 258 11. How to Publish in a Scientific Journal 261 Characteristics of Scientific Journals 262 Business Aspects of Scientific Journals 262 Rankings of Scientific Journals 263 Beginning the Publication Process 267 Choosing a Journal 267 Preparing Your Manuscript 268 Submitting Your Manuscript 270 The Cover Letter 270 Submitting a Manuscript Online 271 Submitting a Manuscript by Mail 273 The Peer Review Process 273 The Editor s Decision 275 The Initial Decision and Peer Review Comments 275 The Final Decision 276

xv The Production Process 279 After Publication 280 Requirements for Articles Reporting NIH-Funded Research 280 Following Up: Who Cited Your Article? 281 A Note for Non-Native English Speakers 282 Part III: How to Present in the Health Sciences 287 12. How to Prepare and Present a Scientific Poster 289 An Overview of Poster Displays 290 The Call for Abstracts 290 Human Factors in Poster Viewing 290 Preparing the Poster 292 Scheduling and Planning 292 Writing the Text 293 Preparing the Illustrations 297 Format and Construction 299 Designing the Layout 300 Choosing Type Fonts and Sizes 301 Using Color 309 Other Considerations 309 What to Do at the Conference 310 Setting up the Poster 310 Presenting the Poster 310 Removing the Poster 311 13. How to Prepare and Present Slides 313 Communicating with Slides 314 Designing Slides 315 Presentation Software Programs 315 Slide Formats 315 Choosing Type Fonts and Sizes 316 Formatting the Text 317 Using Color 322 Other Considerations 324 Preparing Images 326 Visual and Audio Effects 330 Organizing and Writing the Text 333 Software Considerations 336 Hardware Considerations 340 Delivering Your Lecture 340 Your Spoken Presentation 340

xvi Handouts: Your Written Presentation 341 Other Considerations 345 Appendix: The Value of Systematic Reviews as Research Activities in Medical Education 349 Index 361 About the Author 387