MC-500 Vixi MC-500. Multicolor Scan Laser Photocoagulator. Multicolor Laser Photocoagulator US EDITION

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Multicolor Scan Laser Photocoagulator MC-500 Vixi MC-500 Multicolor Laser Photocoagulator US EDITION

MC-500 / MC-500 The Versatile Laser Photocoagulator The versatility of the MC-500 Vixi / MC-500 speaks for itself. The multiple functions of the MC-500 Vixi / MC-500 meet every requirement for laser photocoagulation. Selectable configuration of laser colors and delivery units Multiple scan patterns Enhanced usability The MC-500 Vixi / MC-500 provides various laser treatments including panretinal photocoagulation for diabetic retinopathy and laser iridotomy for glaucoma with a slit lamp delivery unit, retinal photocoagulation for retinopathy of prematurity with a BIO delivery unit, and endophotocoagulation via a probe.

Multicolor on Modular Architecture Multicolor Laser for Multiple Applications The MC-500 Vixi / MC-500 enables efficient photocoagulation even through opaque media. In cases of cataract, better penetration is achieved with the yellow (577 nm) laser compared to the green (532nm) laser. In eyes with retinal hemorrhage, better penetration is achieved with the red (647 nm) laser. 532 nm The 532 nm (green) is the most common wavelength for treating retinal pathology. 100 Absorption rate (%) 577 nm The 577 nm (yellow) laser is minimally absorbed by xanthophyll and is well absorbed by oxygenated hemoglobin compared to 561 nm and 568 nm lasers making it the wavelength of choice for lesions close to the macula. This wavelength has plentiful results achieved with the Dye lasers. 50 647 nm The 647 nm (red) wavelength has been historically used in Krypton lasers. This wavelength is used for photocoagulation of deep choroidal pathology. Pigment epithelium Reduced hemoglobin Oxygenated hemoglobin Xanthophyll 450 500 550 600 650 Wavelength (nm) Reference: Folia Ophthalmol. Jpn. 40(5)1128-1133, 1989 532 nm (MC-500, 300) 561 nm (MC-300) 568 nm (MC-7000) 577 nm (MC-500) 647 nm (MC-500, 7000) 659 nm (MC-300) Selectable Laser Color Configuration The MC-500 Vixi / MC-500, with its user friendly design, allows the selection of one, two, or three wavelengths, among green, yellow, and red. It enables the freedom to select the necessary color or combination of colors to increase efficiency of treatment. Three-color selection Two-color selection One-color selection Green Yellow Red

Multiple Scan Patterns The MC-500 Vixi has 22 preprogrammed scan patterns to allow treatment of varying retinal pathologies. A Triple arc Square (2x2, 3x3, 4x4, 5x5) Triple curve Equal space (2x2, 3x3, 4x4, 5x5) A The scan patterns of photocoagulation laser on retina are simulated. Rectangle Triangle Circle Arc (3/4 circle) Arc (1/2 circle) Arc (1/4 circle) Curve Macular grid* Line Single *The macular grid pattern is used for treatment of the periphery of macula in quadrants. The inner diameter is fixed and spot sizes range from 100 to 200 µm. Typical Scan Patterns Equal space (2x2, 3x3, 4x4, 5x5) The space between spots is equal in all directions. The square pattern makes larger spaces in the diagonal direction than the horizontal and vertical directions. The equal space pattern keeps the spaces between spots equal allowing for denser photocoagulation than the square pattern. Square (2x2, 3x3, 4x4, 5x5) The space between spots is equal in the horizontal and vertical directions. Equal space Square

Auto Forward* Once photocoagulation is completed in one region, the MC-500 Vixi allows automated positioning of the scan pattern to the next region to undergo photocoagulation. This feature allows the surgeon to concentrate on focus adjustment. Selected path - The repeat mode with the auto forward function enables consecutive regions to undergo photocoagulation on a selected path without repeatedly pressing the foot switch. *The auto forward function is available for the equal space (2x2, 3x3, 4x4) and the square (2x2, 3x3, 4x4) patterns. The number of times of the forwarding differs depending on the scan pattern, spot size, and spacing. Spot Spacing & Pattern Rotation The space between spots in the pattern can be changed and the pattern can be rotated (15 increments) easily with the LCD touch screen. Spacing Rotation

Wide Range of Delivery Unit Options In addition to conventional single delivery units the scan delivery units are added to the wide range of multicolor laser delivery systems. Both the scan and single delivery units include attachable models* for NIDEK SL-1800, ZEISS SL130 and 30SL/M, and HAAG 900BQ, which provide the existing slit lamps with a new stage for scan and single laser treatment. *Prior confirmation of existing model s status is necessary for attachable models. Scan Delivery Units (MC-500 Vixi) Scan slit lamp delivery unit (NIDEK SL-1800) Scan attachable delivery unit (NIDEK SL-1800, ZEISS SL130) Scan attachable delivery unit (ZEISS 30SL/M) Slit lamp delivery unit (NIDEK SL-1800) Attachable delivery unit (NIDEK SL-1800, ZEISS SL130) Attachable delivery unit (ZEISS 30SL/M) BIO delivery unit (HEINE OMEGA 500) YAG laser combination delivery unit (NIDEK YC-1800) Scan attachable delivery unit (HAAG 900BQ) Single Delivery Units (MC-500) Dual Delivery Unit Connectors The dual delivery unit connectors enable simultaneous connection with two delivery units, such as slit lamp delivery and BIO delivery units. They eliminate the inconvenience of connecting and disconnecting units and provide easy cable management. Endophotocoagulation delivery unit (ZEISS, LEICA) Front Delivery Unit Connector (optional) The combination of one delivery unit connector in front and one in back is available as a factory option. The front delivery unit connector helps with easy connecting and disconnecting.

SOLIC (Safety Optics with Low Impact on Cornea) All scan slit lamp and slit lamp delivery units including attachable models incorporate the SOLIC optical design that ensures low energy density on the cornea and lens even for large spot sizes. Conventional Small spot Large spot Small spot Large spot Continuously Variable Spot Size The scan spot size is continuously variable from 100 to 500 µm (50 to 500 µm in single mode). The continuous variability enables the surgeon to easily compensate for the spot size change due to the use of a laser contact lens. Momentary increase followed by a plateau and an immediate decrease enables rapid and high-power laser emission on the scan patterns. Power output Stable Laser Power Output Wave profile measured with oscilloscope Emission time 0.02 second Time

Practical and User-friendly Features Intuitive graphic user interface and easy-to-read color LCD touch screen allows easy and quick setup and confirmation of the scan pattern and treatment parameters. Pop-up Window The pop-up window appears once the displayed value, such as POWER, TIME, and INTVL, is touched. It enables the surgeon to make significant changes to the laser values quickly with two-touch operations. Spot Size The spot size of the scan slit lamp delivery unit and slit lamp delivery unit is displayed on the LCD, and can be read with other parameters even in a dark room. Actual Spot Size The converted spot size is displayed once the laser spot magnification of laser contact lens is selected on the pop-up window. 1. Touch the value on the screen 2. Select the value on the pop-up window Memory of Scan Pattern* Four frequently used scan patterns can be saved and recalled with one-touch selection. *Available for the MC-500 Vixi MC-500 Vixi LCD screen This screen displays all buttons and items for convenience sake, but the actual screen is not consistent with this sample screen. LCD Brightness Adjustment When the status is switched from standby to ready the LCD brightness decreases so that there is no interference with the surgeon s visibility of ocular pathology during treatment. STANDBY READY

Multifunctional 3-D Mouse (optional) The multifunctional 3-D mouse allows intuitive operation to change the parameters. Up to 10 parameters among 19 can be set with the multifunctional 3-D mouse. Control Box (optional) The power knob on the control box adopts a user-friendly dialing feature. Turning the knob enables change of the output power by 10 mw (up to 500 mw ) or by 50 mw (higher than 500 mw). Turning and simultaneously depressing the knob enables to change by 100 mw. Remote Control (optional) The handheld remote control is useful to control output power and other parameters remotely. The phosphorescent panel provides visibility in the dark room during vitreoretinal surgery. Memory of Photocoagulation Data In accordance with various clinical cases up to 10 sets of photocoagulation data (color, power output, emission time, interval time, scan pattern, and spacing) can be registered. Each set is retrievable quickly with one-touch operation.

Case of Panretinal Photocoagulation for Severe Non-Proliferative Diabetic Retinopathy Total surgery time 24 minutes Laser contact lens Mainster PRP 165 (1.96x) Wavelength (color) 577 nm (yellow) Scan pattern Square (2x2, 3x3, 4x4) Spot size 200 µm Spacing 0.5, 0.75 Power output 300-450 mw Emission time 0.02 second Shots 4,772 Color fundus image after photocoagulation Total energy 42.4 J FA image after photocoagulation Photo courtesy of Prof. Murata, Shinshu University The case above is an excerpt from the case report of the multicolor laser photocoagulation with the MC-500 Vixi.

MC-500 / MC-500

Main Body Specifications Power output Output type Emission time Interval time Aiming laser Cooling system Power supply Power consumption Dimensions / Mass 480 mm Solid state laser, Diode laser Green : 532 nm Yellow : 577 nm Red : 647 nm Green : 50 to 1700 mw *1 Yellow : 50 to 1500 mw Red : 50 to 800 mw *2 Continuous wave 0.01 to 1.00 second, 2.00 seconds, 3.00 seconds *3 0.05 to 1.0 second *4 Red diode, 670 nm, max. 0.4 to 0.8 mw Air-cooled AC 100 to 240 V, 50/60 Hz 400 VA 300 (W) x 480 (D) x 670 (H) mm / 35 kg 11.8 (W) x 18.9 (D) x 26.4 (H) " / 77.1 lbs. 950 mm Laser type Wavelength *1 50 to 1500 mw with scan delivery unit *2 With the slit lamp delivery unit, scan slit lamp delivery unit, attachable delivery unit, and scan attachable delivery unit, the maximum power output is limited according to the spot size. Spot size 50 µm - 500 mw, Spot size 60 µm - 600 mw, Spot size 70 µm - 700 mw *3 0.01 to 0.05 second in scan mode *4 0.3 to 1.0 second in auto manipulation mode and auto forward function Not available in scan mode except single scan pattern and other scan patterns available with auto forward function Foot print Scan / Single Delivery Unit Specifications Model Spot size Emission pattern Type Dimensions / Mass Scan delivery unit (MC-500 Vixi) 100 to 500 µm (scan mode & auto manipulation mode) 50 to 500 µm (single mode) Single Square (2x2, 3x3, 4x4, 5x5), Equal space (2x2, 3x3, 4x4, 5x5), Rectangle, Triple arc, Triple curve, Macular grid, Triangle, Circle, Arc (3/4 circle, 1/2 circle, 1/4 circle), Curve, Line Scan slit lamp delivery unit (NIDEK SL-1800) Scan attachable delivery unit (NIDEK SL-1800, ZEISS SL130 & 30SL/M, HAAG 900BQ) 600 (W) x 450 (D) x 1300 to 1500 (H) mm / Approximately 45 kg *5 23.6 (W) x 17.7 (D) x 51.2 to 59.1 (H)" / Approximately 99.2 lbs. *5 (NIDEK SL-1800 scan slit lamp delivery with table) Single delivery unit (MC-500) 50 to 1000 µm (slit lamp & attachable deliveries) Single Slit lamp delivery unit (NIDEK SL-1800) Attachable delivery unit (NIDEK SL-1800, ZEISS SL130 & 30SL/M) BIO delivery unit (HEINE OMEGA 500) YAG laser combination delivery unit (NIDEK YC-1800) Endophotocoagulation delivery unit (ZEISS, LEICA) (NIDEK SL-1800 slit lamp delivery with table) *5 The dimensions and mass differ depending on delivery types. LASER RADIATION AVOID EYE OR SKIN EXPOSURE TO DIRECT OR SCATTERED RADIATION LASER LIGHT - AVOID EYE OR SKIN EXPOSURE TO DIRECT OR SCATTERED RADIATION CLASS 4 LASER PRODUCT MAXIMUM OUTPUT : 3W, CW WAVELENGTH : 532 / 577 / 647 / 670 nm CLASS IV LASER PRODUCT MAXIMUM OUTPUT : 3W, CW WAVELENGTH : 532 / 577 / 647 / 670 nm IEC 60825-1 2007 Product / Model name: Multicolor Laser Photocoagulator MC-500 Caution: U.S. Federal Law restricts this device to sale, distribution, and use by or on the order of a physician or other licensed eye care practitioner. Specifications may vary depending on circumstances in each country. Specifications and design are subject to change without notice. HEAD OFFICE 34-14 Maehama, Hiroishi Gamagori, Aichi 443-0038, Japan Telephone : +81-533-67-6611 Facsimile : +81-533-67-6610 URL : http://www.nidek.co.jp [ Manufacturer ] TOKYO OFFICE (International Div.) 3F Sumitomo Fudosan Hongo Bldg., 3-22-5 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Telephone : +81-3-5844-2641 Facsimile : +81-3-5844-2642 URL : http://www.nidek.com NIDEK INC. 47651 Westinghouse Drive Fremont, CA 94539, U.S.A. Telephone : +1-510-226-5700 : +1-800-223-9044 (US only) Facsimile : +1-510-226-5750 URL : http://usa.nidek.com NIDEK S.A. Europarc 13, rue Auguste Perret 94042 Creteil, France Telephone : +33-1-49 80 97 97 Facsimile : +33-1-49 80 32 08 URL : http://www.nidek.fr NIDEK TECHNOLOGIES Srl Via dell'artigianato, 6 / A 35020 Albignasego (Padova), Italy Telephone : +39 049 8629200 / 8626399 Facsimile : +39 049 8626824 URL : http://www.nidektechnologies.it NIDEK JANUARY 8, 2016 16-0002