How to get the best out of presubmission enquiries

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Caroline Halford, Adis Publishing Manager MedComms Networking Event, 4 January 2017 www.medcommsnetworking.com How to get the best out of presubmission enquiries

All authors want timely publication but there are many challenges ALLTRIALS! Authors currently on the 7 th draft taking forever GPP3: Submit manuscript 12-18 months after LPLV Client wants a manuscript published in time for ESMO Been rejected 4 times already. What now? PUBLICATION PLANNERS AND MED COMMS Which journals publish sponsored reviews?

My job was created to solve this problem I need to publish this manuscript. PUBLICATION PLANNERS OR MED COMMS Send me the details and I ll ask the Adis editors if they d consider publishing it ME AT ADIS HQ (PART OF SPRINGER NATURE)

My job Hi Editors what do you think about this article? No thanks Maybe. If the limitations were expanded to discuss X? Yes please! ME AT ADIS HQ (PART OF SPRINGER NATURE) ADIS EDITORS-IN-CHIEF

Success! Dear Dr Smith. We are pleased to tell you that your article has been published in CNS Drugs. PUBLICATION PLANNERS AND MED COMMS

It is not uncommon to receive vague information about manuscripts?? We have health outcomes data around my new product will this be suitable for PharmacoEconomics? I have a study of patients treated with statins.. Which Adis journals will be likely to accept it????? My client needs to publish a review on new heart failure agents

Help editors to help you There are several tools to help authors choose a realistic/suitable journal Journal selector tools Analysing journal rejection rates Engaging the author in a presubmission conversation is often the best way to receive personalised advice on your article s suitability Vague presubmission enquires do not allow editors to give you accurate advice The more information you can provide in a presubmission enquiry = the better the chance of an accurate response on your manuscript s suitability for publication

Rejection rate can be a starting point Rejection rate: 95% Rejection rate: ~30%

Beware of putting too much trust into a journal s rejection rate Case study: Clinical Drug Investigation One of Adis most famous journals Impact Factor 1.806 Broad aims and scope Welcomes all kinds of research regarding clinical trials (including HEOR, PK/PD, etc) Rejection rate 65% BUT. This is partially because it receives so many out-of-scope articles (such as preclinical studies and case reports! ) Other journals may have low rejection rates, but this may be because it is a niche field with few submissions

Journal shortlist tools can be helpful to make a shortlist Many services now available to help identify suitable journals, (e.g. Edanz, DataVision, PubsHub) There are also semantic technology tools to help you choose from over 2,600 journals. Enter the abstract, description of the research, or a sample text. Refine the results based on requirements But these tools can have limitations Data may not be up-to-date Matching up keywords can pull up journals that are not a good fit

Editors want good manuscripts Increased subs Increased market awareness Good articles The virtuous circle Improved journal profile Article usage Citations (Impact Factor)

What is a good manuscript? Fits scope of the journal Not replicating other recent content within the journal High enough interest Describes research that might affect future research/treatment (positive, negative, neutral, confirmatory data) Is it a review of an area that has not been covered before/recently? Has novel findings, or at least adds something new to the literature? Has robust methodology Is fair/balanced Uses clear and concise language Timely All these factors can lead to high readership and citations (and feed the virtuous circle) It is almost impossible to tell if a manuscript fits the above criteria from a one-line presubmission enquiry Good articles

Reasons editors might decline to send your paper to peer review Published a similar paper recently (or have one in the pipeline) Not of high enough interest to readers (i.e. will not provide adequate readership/citations) Too much copy The paper is not carefully prepared and formatted No evidence of ethical approval (for ORAs) Trial not prospectively registered Too perceivably promotional (reviews or interpretation of ORA results) Badly written/needs editing work The template rejection email will be unlikely to give you this information However, an editor will often give this feedback during a presubmisison conversation which may help you to in your next journal choice Either by fixing the issues raised Or choosing a more inclusive journal

Common reasons for rejection after peer review Methodological flaws (ORAs) Significant data omitted (reviews) Fabricated/manipulated data Salami slicing Over-stating conclusions Plagiarism (ithenticate plagiarism checker software) Editors respect and rely on reviewers independent, expert opinions regarding data Nevertheless, if you send the editor a full draft, they can often advise you on these issues beforehand, allowing you to address them before submission Methological issues can sometimes be addressed in the limitations Plagiarism can be easily fixed

Honesty is the best policy regarding previous rejections Always declare the manuscript s submission history in a presubmission enquiry (or within the official submission) A previous rejection does not mean the next editor will necessarily reject it But not declaring it can make editors and peer reviewers look unfavourably on your work Your manuscript may be sent to the same reviewers that have previously rejected it and these reviewers may be annoyed if authors have not taken on board any of their comments A soft indicator for editors - what else have the authors not been transparent about? By discussing the manuscript history with the editor in a presubmission enquiry, the editor can provide advice about: Which previous journal comments should be addressed Which comments can be rebutted within the new manuscript Occasionally, previously peer reviewed manuscripts do not need further review

What to include in presubmission enquiries Best-case scenario = send the full paper (essential for HEOR) Cover letter describing how the article adds to the literature If unable to provide the full text, please provide the following for original research: Clinical trial registration number Title + abstract + authors Funding For reviews: An unfinished draft is ideal Outlines may also be sufficient for the editor to assess suitability Or at the least, provide a good description of the scope/type of review Funding For case reports: as much detail as possible! For all papers: include history of the paper + what looking to achieve (timelines)

Conclusion Journals want to publish good manuscripts Good means different things to different editors Nevertheless, editors generally want readership and citations: manuscripts that will add to the literature (rather than replicate it) The editor is best placed to advise you on if your paper is of interest to their journal Therefore: üprovide as much information as possible in the presubmission enquiry übe transparent about the history of the article üaddress the previous journal s comment s as much as possible or provide detail in the cover letter as to why you haven t ünowadays, many journals will have cascading titles to find a home for your work

Please contact me if you have any questions Caroline Halford Adis Springer Healthcare Ltd Adis Publishing Manager --- Springer Healthcare Ltd Chowley Oak Business Park Tattenhall Chester CH3 9GA, UK Tel: +44 (0)1829 772741 E-mail: caroline.halford@springer.com --- www.springer.com/adis and www.adis-rapidplus.com Follow us on Twitter: www.twitter.com/adisrapidplus or www.twitter.com/adisjournals