Assessment & management of irregular astigmatism

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Assessment & management of irregular astigmatism Athens, March 2018 D. Epstein, MD, PhD, FARVO

No financial interest

What is an irregular astigmatism? A question that starts at the wrong end... How about defining regular astigmatism?

What is a regular astigmatism? The meridians of the maximum and minimum curvature of the cornea are at right angles

What is an irregular astigmatism? When the two principal meridians of the cornea are not at right angle to each other

Two types of irregular astigmatism Regularly irregular Identifiable pattern (e.g. asymmetric bowtie) Irregularly irregular No recognizable pattern on corneal topography

PMD

Iatrogenic ectasia

Preop 3 months 7 months

DD: iatrogenic ectasia

Irregular astigmatism Cannot be corrected with spherocyl lenses Correction: RGP CLs, sclerals or surgery

Irregular astigmatism is all around us Post corneal/refractive surgery, keratoconus, other corneal pathology, post trauma, post RGP Even regular can have an irregular component May be missed before toric lens implantation

Identifying irregular astigmatism Topography, tomography, wavefront But it is still permitted to use common sense: To get a general sense of the magnitude of any irregular astigmatism, test the difference between spectacle and RGP visual acuity

Therapy options RGP CLs and scleral lenses Topography-guided ablations (± CXL) Toric IOLs (makes no sense?) Intacs, DALK/PK, pinhole sulcus implant

Contact/scleral lenses RGP corneal CLs Hybrid (RGP center, soft skirt) Scleral/mini scleral lenses

Contact/scleral lenses Mask irregularities regular refractive surface RGP: fitting approaches/peripheral curves Scleral: excellent in advanced ectasia, when intolerance to CL No corneal touch, good centration and VA

Irregular astigmatism and CLs RGPs remain the first choice for correcting irregular astigmatism For the majority of such patients, it is the optimal solution for their visual problems

Topography-guided ablations For irregular astigmatism after refractive surgery (excentric ablations, small optical zones) Also for post-pk, scars, trauma, KC Not for thin corneas (<400μ), unstable ectasia, deep scars ( DALK, PK) BUT topo-guided PRK with CXL for ectasia

Topography-guided ablation Courtesy G Kymionis

Post-penetrating keratoplasty irregular astigmatism Topo-guided PRK+MMC Difference map Pre Post

TOPO-GUIDED PRK - CXL

THERE ARE STILL IRREGULAR CORNEAS IN WHICH TOPO-GUIDED ABLATION IS NOT APPLICABLE: Very thin corneas less than 400 μm INTACS implantation / DALK or PK Deep corneal scar DALK or PK

Toric IOLs in irregular astigmatism How in the world can an IOL correct an irregular cornea? Since the cornea is the cause of the irregular astigmatism, what s the point of an IOL?

Toric IOLs in irregular astigmatism The toric IOL corrects the regular component of the astigmatism (most patients have some of both) If the irregular component is minor, a satisfactory visual result can still be obtained Pseudophakic, phakic and piggy-back variants

Toric IOLs in irregular astigmatism Young KC patient, still with low degree of irregular astigmatism Can be stabilized with CXL Then a RGP lens can be worn If CL intolerance develops phakic toric IOL (the CXL may prevent further irregularity)

A new and promising approach Customized CXL for KC Only the relevant tissue is treated

Customized Corneal Cross-linking Strengthens only weak parts of the KC cornea (more energy needed where weak) Customized CXL as safe as standard CXL More flattening of Kmax, faster epi healing

Customized Corneal Cross-linking: One-Year Results Kmax decreased by 3.6D AJO, 2016

Standard Corneal Cross-linking: One-Year Results Kmax decreased by 0.8D AJO, 2016