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Medical Laser LLLT CLINICAL RESEARCHES AND TREATMENT PROTOCOL r n 7 M'e/*a l{*/il @ - //// //r6/lbrn4 l.tu /' l'/ Ph 04 5653211. Fax 04 5653219. Mob 021 668 ZO4 11 Tarras Grove, Ketson, Lower Hutt 5010, New Zeatand Email. sales@beurerproducts.co.nz Website www. beurerproducts.co. nz ESENLER GRUP

TABLE OF CONTENTS Alternative Solution In Tinnitus Treatment Study 1. The Role of LLLT in Treatment of Tinnitus study 2. comprehensive therapy of patients suffering from tinnitus study 3. comprehensive taser Rehabilitation Therapy of Tinnitus Therapy: LLLT - Physiotherapy aimed at the initial organ of hearing Study 4. Tinnitus and vertigo Study 5. Transmeatat cochlear laser (TcL) treatment of cochlear dysfunction: a feasibility study study 6. low-energy laser radiation in the combined treatment of sensorineural hearing loss study 7. Light dosimetry and preliminary clinical results for low level laser therapy in Study 8' Infrared laser apptied into the meatus acousticus Study 9. Ex-vivo laser penetration study Study 1O. Average duration of tinnitus of 1O years

Buyukdere Caddesi No: 10/4A Sisli, 34360, Istanbul, TURKEY Tch +90 212291 83 83 Fax, +9O 2L2 233 50 94 info@od iomed.com www.odiomed.com odiomed has been offering tinnitus pen to its tinnitus patients since the beginning of 2008 and-2009. We received significant reiults from our tinnitus pen users. 2,540 people with chronic tinnitus for over 6 months at a level of effecting their casual life, got tinnitus pen from us. Results are as belsw; Our patient group consists of 2.540 people' t,575 males (680/o1,965 females (32o/o)' Age is ranging between 2O to 72 years. After using the tinnitus pen 10 minutes for one ear a day for 90 days, here are the results they provide; Result # Patients Percent No more tinnitus 1.158 0/o46 More than 50 o/o relief 356 o/ol4 [-ess than 5O olo relief 229 o/o9 No effect 787 o/o3t TOTAL 2.549 olot00,a 1,168 users (A6o{rol declared that they do not suffer from tinnitus anymore 356 users (1.4o/o) ieclared that their iinnitus decreased to a level that can easily be ignored- 229 users (9o/o) declared that their tinnitus decreased to a level that enables them to socialize but still have problems in silent environments' 1sz u,u"ri (3La/o) deilared that there has been no change with their tinnitus problem'

The Role of LLLT in Treatment of Tinnitus Laser Partner, 26.2.2002, Miroslav Prochazka, M.D., Head doctor of the Jarov Rehab Cllnic, Prague Abstract Comprehensive laser rehabilitation therapy of tinnitus has proven successful and beneficial for treatment of this widespread civilization disease. Its long-term results are convincing, bringing significant relief to 36 per cent of patients and even leaving remarkable 26 per cent of patients without any symptoms (see Miroslav Prochazka, Ales Hahn: Comprehensive Laser Rehabilitation Therapy of Tinnitus: Long-Term Double Blind Study on a Group of 200 patients in 3 years, Laser Partner No. 51/2002). With the results mentioned above we can really speak about a breakthrough. This study brings an additional overview of the role of LLLT (Low Level Laser Therapy) in the treatment. our results enable us to pinpoint laser as the leading element in the overall therapy of tinnitus. Introduction Tinnitus is an auditory perception appearing without an objective sonic source from the outer environment. Tinnitus can be subjective (heard only by the patient) and objective (sound can be even heard also by others). Our study, however, deals with patients suffering from subjective tinnitus only. According to literature, fifteen per cent of entire population have experienced at least a tinnitus episode some time, its incidence and severity rising with age up to approx. eighty-five per cent of population older than 60. our clinic has been treating tinnitus for more than 5 years. We have published three studies on this particular issue, and we are of the opinion that our results are being followed in several countries (Brazil, cyprus, sweden, switzerland, slovakia, Turkey, Japan, Germany etc') and implemented in numerous clinics with significant results. Studies published by these clinics show results which are almost identical with our experience' Our last study on a group of 200 patients in the course of three years was finalized in February 2OO2 and published in lune 2002. Since there have always been efforts to evaluate an exact role of LLLT in treatment of tinnitus, apart from medication and physiotherapeutic manipulation of neck vertebra as an integral part of the comprehensive therapy, we have decided to create a separate group of patients to be treated only with laser' This was only possible thanks to our vast experience and long involvement in tinnitus treatments.

Materials and methods Our group consisted of 72 patients, 49 males, 23 females, age ranging between 16 to 92 years. The age and sex is given in Table 1 Table 1. Distribution of Sex/Age sex / AGE 16-20 21-30 31-40 41-50 51-60 61+ l{ale 2 4 6 9 t3 15 Female o 1 4 5 6 7 TOTAL 2 5 10 L4 19 22 Diagram 1. Distribution of Sex/Age 16 14 12 10 8 6 El tale I Fenrale 4 2 o prior to the application of LLLT, atl the patients undelwent the following pre-therapy examination: 1, Anamnesis (aimed especially at the fact whether tinnitus was caused by an acoustic trauma, as well as at genetic predisposition) 2. Subjective evaluation of suffering 3. Clinical examination (otoneurotogy, axial skeleton, nystagm, blood pressure)