Capsule Filling and Closing Machine GKF 2500 ASB - GKF 2500 ASB IPK - GKF 2500 ASB 100%
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1 Capsule Filling and Closing Machine GKF 2500 ASB - GKF 2500 ASB IPK - GKF 2500 ASB 100% 1
2 Optimized productivity through automation The GKF 2500 series of machines with automatic troubleshooting system (ASB) ensures optimized productivity and pharmaceutical security for the filling of capsules. Versions GKF 2500 ASB, GKF 2500 ASB IPK or GKF 2500 ASB 100 %. 2
3 GKF 2500 ASB 100% with online weight control and optional tablet station The high degree of automation ensured by ASB provides for smooth production processing and ensures optimized productivity with minimum downtimes. The GKF 2500 ASB IPK with in-process control makes it possible for you to perform weight control by way of statistical evaluation with documentation of the random sample data, daily data and batch data. The GKF 2500 ASB 100 % is equipped with an integrated checkweigher. Each capsule is weighed individually and with high precision. Accepted are only those capsules of which the weight is within the preset tolerance limits. Any overweight or underweight capsules are rejected. 3
4 4 Easy operator control Optimized sealing technology Easy cleaning
5 Secure investment and production High-precision dosing for powder and pellets Wide range of dosing facilities, e.g. with optional tablet station Data security Consistently cgmp-compliant High-precision dosing Control and measured data acquisition design Proven dosing of powders on the tamp- are performed via an industrial PC. All The table top is made from one piece ing pin principle via the dosing disk. production data are stored and managed of material with no joints. With large Constant improvements have consid- here. The WINDOWS-based software chamfer radii and no undercuts. A erably enhanced the efficiency of the meets the requirements of 21 CFR part high-grade coating seals the surface system. Pellets and other non-tampable 11 for data security. smoothly and free from pores. Special products can be filled particularly gen- shaft seals separate the production tly via the dosing disk. The fill volume Easy operator control area from the drive area and prevent is adapted optimally to the amount of Operator control of the machine via foreign substances from getting into product by means of the height-adjust- touchscreen is very user-friendly. Posi- the product. able dosing disk. the user-friendly and easy-to-learn Low-maintenance operation Wide range of dosing facilities menu guidance via self-explanatory Encapsulated drive elements ensure The capsule is filled with other prod- symbols. that the lubricants cannot get into the ucts such as tablets, coated tablets tive points for the operating personnel: environment. The low-maintenance belt or pellets via additional, optional dos- Optimized accessibility drive provides for quiet running of the ing stations. Difficult products do not The production area is clearly and tidily machine, reduces wear and thus present a problem either. Make use of arranged. All stations are freely accessible thanks to the upward swiveling extends the entire service life. our experience. We shall be glad to give you our advice. guard doors. The ergonomic design of the machine and effortless disassembly of the stations contribute towards easy handling. This also means size-changing and cleaning without difficulty. 5 5
6 Functional diagram of the 100 % weight control Functional diagram of the GKF 2500 ASB 1 Capsule container 2 Insertion pusher 3 Rear wall of magazine 4 Size plate 5 Singularization flaps 6 Conveying lug 7 Weighing cells 8 Clearing starwheel 9 Discharge flaps 1 Capsule alignment and separation 2 Capsule alignment and separation 3 Capsule cap scanning (ASB function) 4 Free for the optional pellet station 5 Dosing station for powder or pellets via a fixed or height-adjustable dosing disk 6 Free for the optional pellet station 7 Extraction for non-opened capsules 8 Free for the optional pellet or tablet station 9 Capsule closing station with the ASB body scan function 10 Individual capsule discharge (ASB function) 11 Individual capsule discharge (ASB function) 12 Segment cleaning with compressed air (ASB function) 6
7 Empty capsule feed and separation (stations 1 and 2) with mechanical capsule cap scanning (station 3) Individual capsule discharge (stations 10 and 11) Reliable production through ASB The automatic troubleshooting during production makes possible automated production and reduces downtimes. The calibration bar in the empty capsule magazine ensures that deformed or damaged empty capsules are already discharged before the filling process. The mechanical capsule cap scanning facility detects blockages in the capsule feed. The repeated occurrence of missing capsules in a segment bore is detected by the serial fault function. Any deformed capsules in the capsule magazine are blown out by means of a targeted pulse of compressed air and then collected in a bin. The capsule body scanning facility detects incomplete capsules during the closing process. No powder or capsule parts get into the production batch. Defective capsules are individually discharged via the 18 discharge flaps. The segment cleaning with blow nozzles reliably releases any adherent product and capsule remains from the segment borings and discharges these by means of suction air. This ensures thorough cleaning of the segments. 7
8 GKF 2500 ASB dependable production In addition to the advantages of the ASB system the integrated weighing systems provide you with a dependable and documented production procedure. GKF 2500 ASB 100 % with online weight control Each capsule is weighed individually with high precision on the integrated control unit, providing high quality and a high yield for your production. The tamping pin pressure is automatically readjusted by an integrated weight readjusting facility with a pneumatic adjuster. In this way it is ensured that the dosing weight remains within the required tolerance limits throughout the production process. The evaluation software computes a mean value from the measured values and makes a target/actual comparison. If the tolerance limit is exceeded, the capsules are discharged. Intervention is recorded in the production report. The high-precision gravimetric weighing cells reproducibly determine precisely and absolutely the weight of the filled capsules. This principle compensates external influences, i.e. ensuring weighing precision. GKF 2500 ASB lpk with in-process control Random samples are removed consecutively from the filling process and weighed at preselectable intervals. The scope of the random sampling is defined by the user. The evaluation software computes a mean value from the individual measured values and makes a target/actual comparison. If the mean values of several random samples infringe the tolerance limit, the tamping pin pressure is automatically adjusted by the pneumatic tamping pin adjuster. Intervention is recorded in the production report. After weighing, all sampled capsules are collected in a separate container. The individual weights are recorded with their relevant positions in the segment. The weigher is self-taring after each weighing process. Everything from one source To complete the automatic capsule filling line we integrate peripheral devices from leading manufacturers to match your requirements, e.g. automatic product and empty capsule feeds, container changer, capsule deduster or metal detector. Our engineers provide you with advice on how to integrate the line into your production control system and make available the necessary interfaces. Profit from our experience We shall of course be glad to deal with your specific requirements and filling tasks. Our team of experienced designers and application engineers are available to give you our help and advice in this area. Our solutions cover project planning, commissioning, qualification, validation, training and after-sales service. We are your competent contact address when it comes to capsule filling. All this in customary Bosch quality. Weight readjustment with 100 % weighing Weight readjustment with statistical in-process control 8
9 Automatic weight readjustment Precise weight determination by means of gravimetric weighing cells 9
10 Technical specifications GKF 2500 ASB GKF 2500 ASB IPK GKF 2500 ASB 100% Output: Machine cycles: Maximum 150,000 capsules/h Maximum 140 cycles/min. Number of segment bores: 18 Connected loads of the machine: Maximum series fuse: Connected load of the vacuum pump: Vacuum requirement: V +/-10 %, 50 Hz, V +/- 10 %, 60 Hz 3 ph/pe Non-standard voltages Connected loads in total 10 kva 1.85 kw, 50 Hz, 2.2 kw, 60 Hz 50 m 3 /h at -250 mbar 16A Compressed air requirement: 2 m 3 /h at 5 bar 4 m 3 /h at 5 bar 45 m 3 /h at 5 bar Connected load of the dust extractor: V, 50 Hz, 4 kw, V, 50 Hz, 8 kw, V, 60 Hz, 4.6 kw V, 60 Hz, 9.2 kw Suction air requirement: 7.2 m 3 /min 7.2 m 3 /min 12.9 m 3 /min Connections: Compressed air supply Ø13 mm Vacuum connection Ø30 mm Dust extractor connection 2x Ø70 mm Plug receptacle for vacuum pump Plug receptacle for jog cable Plug receptacle for dust extractor Main electrical connection Feeds: Powder feed triclamp DN 150 Pellet/tablet feed triclamp DN 100 Empty capsule feed triclamp DN 100 Weight: approx kg approx kg approx kg Standard equipment: Sizes: Filling options: Accessories: Basic machine with integrated control cabinet and built-in control panel Machine control: industrial PC Empty capsule supply container with minimum and maximum level control Dosing station with fixed or height-adjustable dosing disk and product supply container Product supply container with minimum and maximum level control Adjusting device for reproducible adjustment of the dosing disk Capsule closing station with concave closing pins Cleaning station with plunging blow nozzles and extraction Capsule size set for all popular capsule sizes 00 to 5, DB Pellet station Tablet station for a wide range of tablet shapes Vacuum pump for capsule separation Dust extractor Automatic powder feed Empty capsule conveyor Capsule deduster Metal detector Container changer All right reserved to effect technical modifications. 10
11 Technical specifications GKF 2500 ASB GKF 2500 ASB IPK 2320 GKF 2500 ASB 100%
12 PA/MKT 04/06 1 E werbung@iorio.de Arnold, Deizisau Paper: natural white, without chlorine All rights reserved
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