Speed Sensitivity Resolution All-in-one solutions For applications with imaging challenges, we offer a wide range of solutions.
high-throughput Imaging in Low Light Applications New Generation of Solves Three Main Issues All at Once Time Delay Integration () is an imaging technology that improves the sensitivity by enabling a longer exposure compared to the speed of moving objects. Standard linear sensor cameras create images of moving objects; however, the exposure time is limited by the readout speed of the camera. Standard digital CCD cameras can control exposure time; however, generated images are smeared if objects are moving faster compared to the exposure time. solves these problems utilizing special sensors and readout method. Speed Sensitivity Resolution All-in-one solutions Challenges Solutions We Provide Solutions Making Easier to Apply is a well-known and established technology in the field of industry such as factory automation. However, it is not in the bio-medical field such as fluorescence and microscopy applications. One of the reasons is the availability of sensors fit to the application requirement. The other reason is the requirement of special engineering skills for the implementation of sensors, optics, controlling stages and imaging software. We overcome those issues by offering next generation cameras and solutions of their implementation. solutions We provide a new generation cameras and comprehensive solutions including related technologies. Standard line and sensors are not sensitive enough for low light applications such as fluorescence microscopy. We provide a variety of next generation cameras, which have unique features to realize higher sensitivity, as the core of high-throughput imaging. We also provide related technologies as the solutions to implement into your system. Hamamatsu s comprehensive solutions include everything from cameras and modularization of core technologies to dedicated system products. The strength of Hamamatsu lies in its broad and comprehensive lineup of sensors and related technology. Image acquisition Real-time focusing Image analysis software CAMERA Stage control Hamamatsu provides three types of products through OEM partnerships Appropriate cameras Cameras Optical technology Core technology modules Engine Dedicated system products System We offer a wide range of solutions. Ask us any high-throughput imaging challenges.
For everyone with image-processing concerns solutions Variety of superior scan features from the expertise of Hamamatsu sensor technology Operating Principle of Unique sensors realize both high sensitivity and high speed simultaneously Scanning orientation Camera Perfectly seamless image acquisition with high sensitivity and high speed When charges are readout from a CCD, the CCD vertically transfers the charges line by line. If the charge transferring speed and the object moving speed are matched perfectly, it enables the exposure time for the moving object to be as long as the charge transferring time of the vertical stages in the CCD. This method is called, the technology that captures the image of a moving object with high speed and high sensitivity. motion Line scanning makes scanning faster Signal intensity The scanned object moves constantly, and the signal is reinforced at each stage by integrating the signal. This leads to fast and sensitive scanning. Image composition The image is scanned line by line. Fast scanning and 1D composition New fields, new potential Higher throughput Until now, technology has only been used in a limited range of fields. Hamamatsu provides solutions to utilize in a wider range of fields. This technology is more beneficial when the application requires high-throughput imaging which could not be reached by conventional imaging techniques. High-speed, high-resolution imaging of weak light High-sensitivity detection of small objects on an inspection line DNA microarray imaging Requirement : Fluorescence at a high throughput Dust detection on FPD surface Requirement: Detecting dust and scratches on the FPD at higher throughput Increasing excitation light power will deteriorate the fluorescent stains. The light scattering from small objects is very weak. Fluorescence signal decreases in high-speed imaging High accuracy and fast scan by imaging The image quality and speed are dramatically increased by imaging! Detect microparticle and improve throughput!
To meet your unique needs, we offer individual cameras as well as core scanning technology packages Cameras We offer cameras with a variety of features, such as high speed, high sensitivity, and variety of bandwidth ranges. Hamamatsu offers a wide lineup of cameras. Hamamatsu produces cameras for various needs, from high-speed, high-sensitivity cameras that are ideal for producing images of weak fluorescence, to cameras with high-resolution and low-noise characteristics, to cameras that support a variety of bandwidth ranges from ultraviolet to X-ray. Camera Lineup High Speed, High Sensitivity Camera C10000 Series camera series with a broad lineup, including board-type and high-resolution cameras Maximum line rate: 100 khz (C10000-701) Ultrahigh Sensitivity, Electron Multiplication EM- Camera C9100-16, -17 Ultrasensitive cameras featuring an electron-multiplier CCD with capabilities 3CCD Digital Color X-ray ORCA-3CCD- Camera C7780-20T A 3CCD camera with a total color resolution of 36 bit X-ray Camera C10650 Series, C12200 Series X-ray camera is useful for in-line application requiring high-speed operation with high sensitivity. Low Noise, Versatile ORCA-R2- Camera C10600-10B ( option) The camera featuring -40 C internal cooling and a low noise level of 6 electrons r.m.s. Maximum line rate: 14.285 khz Custom System Example High-speed, high-resolution digital slide scanner NanoZoomer 2.0-HT The picture shows Hamamatsu s high-speed, high-resolution virtual slide scanner, the NanoZoomer 2.0-HT. It is a specialized system for pathological slides. Using this system, you can acquire a 1.9- gigapixel image in approximately 100 seconds. The viewing software enable you to manipulate the images with simple mouse operations. With its image-transfer software, it is a popular tool for telepathology.
R R For everyone with image-processing concerns solutions that include related devices. Engine To meet your unique needs, we offer core scanning technology packages. The engine is the core technology that maximizes the camera s high-performance potential and makes high-speed, high-sensitivity, high-resolution scanning possible. Starting from the camera, we also provide the modules necessary to build a customer s own unique system. Core technology in a engine Example of Engine configuration Light source Slit light option Sample ive lens Camera Motorized xyz stage camera (select an appropriate camera) Sample-stage design (design and create a stage that matches the sample shape) Motorized XYZ stage control (including the stage control software) Optimal illumination and optical technology Development of image-acquisition and analysis software In addition, we provide systems to you as OEM partners. System ( Giga-pix Scanner ) We provide high-performance scanning systems through OEM partnerships. We can enhance engines with additional features to produce systems. In addition to the core scanning technology of the engine, systems include a combination of machinery to transfer slides to the scanning area, body design, and utilities that have been optimized for a specific application. We provide these systems to our customers for use with their brand names through OEM partnerships. Example of Giga-pixel Scanner System (for use with glass slides) Provision of a -centered module Provision of high-performance scanning systems NanoZoomer 2.0-HT can transfer and process up to 210 slides automatically using its cassette holders. Also, it is equipped with the Z-stack feature, which allows you to focus on different depths in the slide of a thick sample. You can scan fluorescent samples by using the NanoZoomer 2.0-HT with optional fluorescence illumination optics. Viewing and Analysis of Digital Slides Sample Frozen section of mouse kidney FluoCells prepared slide #3 ( Invitrogen) Specimen size: 10 mm 7.7 mm Staining Glomeruli and convoluted tubules: Alexa Fluor 488 wheat germ agglutinin F-actin: Alexa Fluor 568 phalloidin Nuclei: DAPI
The best solution in a wide range of applications is offered. High-speed scanning Digitalization of pathological slides You can scan a single pathological slide at a resolution of 1.9 gigapixels in approximately 100 seconds. You can also focus on different depths in the slide of a thick sample. Sensor Wafer and glass inspection Fast, high-resolution and high-sensitivity scanning for large samples Camera Lens Imaging for DNA Ultralow light fluorescence and high-resolution imaging Sensor Lens Detecting dust and scratches on FPD glass You can scan the glass surface of a large sample, such as a flat panel display, quickly and at a high resolution. Sensor Lens Imaging of fast moving samples Flow cytometry Excellent spatial resolution as well as high sensitivity and completely seamless measurement X-ray inspection High-resolution and high-sensitivity in-line inspection Excitation Fluorescence Camera X-ray Source Mounted Board Continuous fluorescence images and intensity can be detected. X-ray Camera Product and software package names noted in this documentation are trademarks or registered trademarks of their respective manufacturers. Subject to local technical requirements and regulations, availability of products included in this promotional material may vary. Please consult your local sales representative. Information furnished by HAMAMATSU is believed to be reliable. However, no responsibility is assumed for possible inaccuracies or omissions. Specifications and external appearance are subject to change without notice. 2011 Hamamatsu Photonics K.K. Homepage Address http://www.hamamatsu.com HAMAMATSU PHOTONICS K.K., Systems Division 812 Joko-cho, Higashi-ku, Hamamatsu City, 431-3196, Japan, Telephone: (81)53-431-0124, Fax: (81)53-435-1574, E-mail: export@sys.hpk.co.jp U.S.A. and Canada: Hamamatsu Corporation: 360 Foothill Road, Bridgewater, N.J. 08807-0910, U.S.A., Telephone: (1)908-231-0960, Fax: (1)908-231-0852, E-mail: usa@hamamatsu.com, Germany: Hamamatsu Photonics Deutschland GmbH: Arzbergerstr. 10, D-82211 Herrsching am Ammersee, Germany, Telephone: (49)8152-375-0, Fax: (49)8152-2658, E-mail: info@hamamatsu.de France: Hamamatsu Photonics France S.A.R.L.: 19, Rue du Saule Trapu, Parc du Moulin de Massy, 91882 Massy Cedex, France, Telephone: (33)1 69 53 71 00, Fax: (33)1 69 53 71 10, E-mail: infos@hamamatsu.fr United Kingdom: Hamamatsu Photonics UK Limited: 2 Howard Court, 10 Tewin Road, Welwyn Garden City, Hertfordshire, AL7 1BW, U.K., Telephone: (44) 1707-294888, - Fax: (44) 1707-325777, E-mail: info@hamamatsu.co.uk North Europe: Hamamatsu Photonics Norden AB: Smidesvägen 12, SE-171-41 Solna, Sweden, Telephone: (46)8-509-031-00, Fax: (46)8-509-031-01, E-mail: info@hamamatsu.se Cat. No. SCAS0057E04 Italy: Hamamatsu Photonics Italia S.R.L.: Strada della Moia, 1 int.6-20020 Arese (Milano), Italy, Telephone: (39)02-935 81 733, Fax: (39)02-935 81 741, E-mail: info@hamamatsu.it DEC/2011 IP (200)