CV David D N Da. University of the Witwatersrand Year obtained: 2005

Transcription

1 Prof David D N Da

2 CV David D N Da 1. General information Title, name and surname: Prof, David Dago N Da Date of birth: 1971/10/19 Citizenship: RCI (Republic of Cote D Ivoire) Professional registrations: SACI, PSSA 2. Contact details Organisation where based: Faculty or School: Faculty Health Sciences: Pharmaceutical Work telephone number: +27 (0) Work fax number: +27 (0) Cell phone number: +27 (0) address: David.nda@nwu.ac.za Website address: Work postal address: Private bag x 6001, Internal Box 304, Potchefstroom South Africa, 2520 Work physical address: Potchefstroom Campus 11 Hoffman Street Potchefstroom Qualifications (Start with most recent) PhD University of the Witwatersrand Year obtained: 2005 MSc University of the Witwatersrand Year obtained: 2001 MSc National University of the Ivory Coast Year obtained: Employment history (From current backwards. Not more than five) Research Associate Potchefstroom Campus of the Current Professor Senior Subject Specialist Potchefstroom Campus of the Postdoctoral Researcher Potchefstroom Campus of the

3 Research Scientist Makromed Manufacturing Ltd Kensinghton, Johannesburg 5. Research expertise Scientific domain: Main research field: Medicinal Fields of specialisation: Medicinal and synthetic chemistry, discovery of novel antimalarials NRF rating and year rated: Y Publications (List publications over the last three years) International publications: Lombard C. Marli, N Da D. David, Tran Van Ba Christophe, Wein Sharon, Norman Jennifer, Wiesner Lubbe, Vial Henri (2013). Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids. Malaria J. 2013, 12: 71. David D. N Da, Marli C. Lombard, Julie A. Clark, Michele C. Connelly, Amy Orcutt, Martina Sigal, Kip R. Guy (2013). Antiplasmodial activity and cytotoxicity of 10βaminoquinolinylethylethers of artemisinin. Drug Res., 63, Theunis T. Cloete, Henk J. Krebs, Julie A. Clark, Michele C. Connelly, Amy Orcutt, Martina S. Sigal, R. Kiplin Guy, David D. N Da (2013). Antimalarial activity of 10-alkyl/aryl esters and -aminoethylethers of artemisinin. Bioorg. Chem., 46, Stefan I. Pretorius, Wilma J. Breytenbach, Carmen de Kock, Peter J. Smith, David D. N Da (2012). Synthesis, characterization and antimalarial activity of quinolinepyrimidine hybrids. Bioorg. Med. Chem., 21(1), Marli lombard, David D N'Da, Jaco C. Breytenbach, Natasha I. Kolesnikova, Christophe T. Van Ba, Sharon Wein, Jennifer Norman, Paolo Denti, Henri Vial, Lubbe Wiesner (2012). Antimalarial and anticancer activities of artemisinin-quinoline hybrid-dimers and pharmacokinetic properties in Mice. Eur. J. Pharm. Sci., 47, Theunis T. Cloete, J. Wilma Breytenbach, Carmen de Kock, Peter J. Smith, Jaco C. Breytenbach, David D. N Da (2012). Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin. Bioorg. Med. Chem., 20, Lezanne van Heerden, Theunis T. Cloete, J. Wilma Breytenbach, Carmen de Kock, Peter J. Smith, Jaco C. Breytenbach, David D. N Da (2012). Synthesis and in vitro antimalarial activity of a series of bisquinoline and bispyrrolo[1,2a]quinoxaline compounds. Eur. J. Med. Chem., 55, Theunis T. Cloete, Carl C. Johansson, David D. N Da, Suman K. Vodnala, Martin E. Rottenburg, Jaco C. Breytenbach and Michael Ashton (2011). Mono-, di- and trisubstituted derivatives of eflornithine: Synthesis for in vivo delivery of DMFO in plasma. ArzneimForsch-DrugRes., 61, Marli C. Lombard, David D. N Da, Jaco C Breytenbach, Peter J. Smith and Carmen Lategan (2011). Synthesis and

4 National publications: antimalarial activity of artemisinin-quinoline hybrids. Bioorg. Med. Chem. Lett., 21, Minette Steyn, David D. N Da, Jaco C. Breytenbach, Peter J. Smith and Sandra Meredith (2011). Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin. J. Pharm. Pharmacol. 63, David D. N Da and Jaco C. Breytenbach (2011). Synthesis and antiplasmodial activity of EG-artemisinin ethers and artemisinin-quinoline hybrids. SA J. Chem., 64, Conferences (Attendance over the last three years) International conferences: Jaco C. Breytenbach, Marli C. Lombard, David D. N Da, Carmen A. Lategan, Peter J. Smith, Henri Vial. Synthesis and biological evaluation of new artemisinin hybrids as antimalarial agents, 4th European Conference on for Life Sciences, 31 August - 3 September 2011, Budapest, Hungary, Abstr. p. 67. Podium presentation Minette Steyn, David D. N Da, Jaco C. Breytenbach, Peter J. Smith, Sandra Meredith, Wilma J. Breytenbach: Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin, 4 th International Symposium on Advances in synthetic and Medicinal, August 2011, St. Petersburg, Russia, Abstr. p Poster. Wilma Breytenbach, David D. N Da, Peter J. Smith, Jaco C. Breytenbach, Minette Steyn, Sandra Meredith: Statistical analysis of the antimalarial IC 50 values of synthesized artemisinin derivatives, 4th European Conference on for Life Sciences, 31 August - 3 September 2011, Budapest, Hungary, Abstr. p Poster Marli C. Lombard, David D. N Da, Jaco C. Breytenbach, Peter J. Smith, Carmen A. Lategan. Artemisinin-quinoline hybrids and hybrid-dimers: Synthesis and in vitro antiplasmodial activity, AntiMal Conference on Antimalarial Drugs:, Development and Future Challenges, March, The Royal College of Physicians, London, UK, Abstr. p. 38. Poster

5 National conferences: David D. D N Da: Synthesis and in vitro antimalarial activity of a series of bisquinoline compounds, 32th Annual Conference of the Academy of Pharmaceutical Sciences of South Africa, Rhodes University, Grahamstown, September Podium presentation Marli C. Lombard, David D. N'Da, Jaco C. Breytenbach, Peter J Smith, Carmen A. Lategan, Henri Vial: Artemisinin-quinoline hybrids and hybrid-dimers: Synthesis, in vitro and in vivo antiplasmodial activity, 6th International Conference on Pharmaceutical and Pharmacological Sciences (ICPPS) on Mind the gap, September 2011, Coastlands Hotel Umhlanga, Durban, South Africa, Abstr. p. 74. Podium presentation Lizanne. van Heerden, David.D. N Da, Jaco C. Breytenbach, Wilma J. Breytenbach: Synthesis and in vitro antimalarial activity of series of bisquinoloine and bispyrrolo[1,2a]quinoxaline compounds, 6th International Conference on Pharmaceutical and Pharmacological Sciences (ICPPS) on Mind the gap, September 2011, Coastlands Hotel Umhlanga, Durban, South Africa, Abstr. p. 60. Podium presentation Marnitz T. Verwey, David D. N Da, Jaco C. Breytenbach and Wilma J Breytenbach: Synthesis and in vitro antiplasmodial activity of acridine-triazine hybrids, 6th International Conference on Pharmaceutical and Pharmacological Sciences (ICPPS) on Mind the gap, September 2011, Coastlands Hotel Umhlanga, Durban, South Africa, Abstr. p. 57. Podium presentation