Biograph Vision See a whole new world of precision

Transcription

1 Biograph Vision See a whole new world of precision and its national implementations and are not yet commercially available in the European Union. Unrestricted Unrestricted Siemens Healthcare Siemens Healthcare GmbH, 2017 GmbH, MI MI

2 Although as a modality, PET/CT has vastly improved the practice of healthcare... we were inspired to make breakthrough improvements that would revolutionize PET/CT by going beyond digital to address our customers needs.

3 Biograph Vision Going beyond digital with the Optiso UDR detector 3.2 mm LSO crystals 249 ps 1 time-offlight 84 cps/kbq 1 effective sensitivity 100% SiPM sensor coverage 1 Optiso UDR Beyond digital and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file. Accuracy Performance Reproducibility

4 Biograph Vision See a whole new world of precision Accuracy to reveal the bigger picture Performance + to maximize efficiency and its national implementations and are not yet commercially available in the European Union. Reproducibility to better understand disease progression

5 We want to help you address personalized medicine by focusing on clinical insights while driving sustainable outcomes Data acquired under IRB-approved protocol. Data on file. Biograph Vision and its features and applications and are currently under development and are not for sale in the U.S. Their future availability cannot be guaranteed. They do not yet fulfill all the essential requirements according to the European Medical Device Directive (93/42/EEC) and its national implementations and are not yet commercially available in the European Union.

6 Get the full potential out of your PET/CT with new options X Onco Freeze Static OncoFreeze Dual gating Cardio Freeze CardioFreeze 1 Images virtually free of motion Additional parameters for more information related to therapy effectiveness Absolute quantification 2 FlowMotion Multiparametric PET Suite 3 Biograph Vision, OncoFreeze, CardioFreeze and FlowMotion Multiparametric PET Suite are currently under development and are not for sale in the U.S. Their future availability cannot be guaranteed. They do not yet fulfill all the essential requirements according to the European Medical Device Directive (93/42/EEC) and its national implementations and are not yet commercially available in the European Union. 1 Data courtesy of University of Tennessee, Knoxville, USA, 2 Data courtesy of University of Michigan, Ann Arbor, USA, 3 Data courtesy of University of Geneva, Geneva, Switzerland. All images were acquired on a Biograph mct system.

7 Proprietary LSO crystals LSO scintillator for fast time-of-flight and excellent image quality 1 Siemens is the only PET manufacturer that owns the entire manufacturing process of the detector. Grown, cut, and individually selected inhouse Self-manufactured to enable precise specifications and complete detector redesign and its national implementations and are not yet commercially available in the European Union.. 1 Compared to BGO scintillators.

8 Reducing crystal size improves spatial resolution and contrast recovery, thus improving detectability 3.2 mm LSO crystal element Biograph Vision 5 mm sphere 5x5 crystal mini-block High-resolution torso phantom Sphere size (mm): 5.0, 7.9, 9.9, 12.4, 15.4, :1 contrast-to-background and its national implementations and are not yet commercially available in the European Union. Based on internal measurements available at time of publication. Data on file.

9 All planes of a modified Defrise phantom are clearly visible with Biograph Vision, even off-center Axial resolution phantom Central position Biograph Vision 5 mm 4 mm 3 mm 20 cm off center 5 mm 4 mm 3 mm and its national implementations and are not yet commercially available in the European Union.

10 Clear visualization of the 2.4 mm cylinders of the Mini-Derenzo phantom with Biograph Vision Diameter (mm) Biograph Vision and its national implementations and are not yet commercially available in the European Union.

11 SiPMs cover 100% of the LSO array, maximizing the detection of light from the scintillator More coverage equals faster time-offlight 100% coverage 1 of the LSO array 249 ps timing resolution 1 Time-of-flight performance depends on collecting light from all photons in the scintillation. SiPMs cover the entire LSO-array area, maximizing the detection of light from the scintillator 100% coverage, enabling fast temporal resolution 1 and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file.

12 Stable time-of-flight performance over a large activity range 600 Timing resolution and activity 100% coverage 1 of the LSO array 249 ps timing resolution 1 Timing resolution 1 (ps) Activity (mci) and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file.

13 Time-of-flight performance at 249 ps enables small segments of response 100% coverage 1 of the LSO array 249 ps timing resolution cm 249 ps and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file.

14 A new approach to detector design with Biograph Vision 3.2 mm LSO crystal element 100% coverage 1 of the LSO array 5x5 crystal mini-block and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file. 608 electronic channels

15 Optimal performance in a wide range of count rates with the new Optiso UDR detector Optiso Ultra Dynamic Range (UDR) Fast time of flight and high effective sensitivity provide excellent performance in low and medium activity ranges such as 90 Y, 18 F and 68 Ga applications. A small block detector with low deadtime makes it suitable to operate in the highactivity concentrations found in studies with very short-lived tracers, such as 82 Rb and 15 O. 18 F: Data courtesy of Kantonsspital Baselland, Liestal, Switzerland 11 C: Data courtesy of Zentralklinik Bad Berka, Bad Berka, Germany 82 Rb: Data courtesy of Central Manchester University Hospitals, Manchester, UK Images for illustration purposes only. Data acquired on Biograph mct system. and its national implementations and are not yet commercially available in the European Union.

16 A completely new high-performing detector with the vision of expanding clinical and research capabilities A complete redesign of the PET detector focusing on: Accuracy Performance Reproducibility The new Optiso UDR detector and its national implementations and are not yet commercially available in the European Union.

17 Biograph Vision shares the solid foundation of Biograph mct s clinical workflow and software X Large 78 cm bore FlowMotion continuous bed motion And new, unique features and its national implementations and are not yet commercially available in the European Union.

18 Large bore improves access and comfort 78 cm and its national implementations and are not yet commercially available in the European Union.

19 Designed to support a broad patient population 227 kg maximum patient weight m scan range 1 and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file.

20 High spatial resolution throughout the field-of-view 6,0 Biograph Vision FWHM (mm) 1 5,0 4,0 3,0 2,0 1,0 1 cm 10 cm 20 cm 10 cm 1 cm 0,0 FBP FBP OSEM OSEM 20 cm Axial Transverse Axial Transverse 1 cm 3,9 3,8 3,6 3,4 10 cm 4,8 4,6 4,0 3,9 20 cm 5,1 5,1 4,7 4,1 cannot be guaranteed. They do not yet fulfill all the essential requirements according to the European Medical Device Directive (93/42/EEC) and its national implementations and are not yet commercially available in the European Union. Data courtesy of the Ohio State University, Columbus, Ohio, USA. Data acquired on a Biograph mct system. 1 Based on internal measurements available at time of publication. Data on file.

21 Biograph Vision s high performance enables low injected dose and short scan time 86 cps/kbq effective sensitivity 1 Low injected dose Short scan time and its national implementations and are not yet commercially available in the European Union. 1 Based on internal measurements available at time of publication. Data on file.

22 Biograph Vision Neurology Sharply delineated cortical uptake, with high contrast between the gray and white matter. There is impressive definition of the gyri, basal ganglia and cerebellum. Data acquired under IRB-approved protocol. Data on file. and its national implementations and are not yet commercially available in the European Union.

23 Biograph Vision Oncology Sharp delineation of the muscle and fat planes, vertebral margins and end plates, biliary radicals, renal calyces, aortic wall and papillary muscles of the heart. Data acquired under IRB-approved protocol. Data on file. and its national implementations and are not yet commercially available in the European Union.

24 Biograph Vision Cardiology Visualization of the heart with impressive clarity, including remarkable delineation of the left ventricular edge and papillary muscles even without cardiac gating. Data acquired under IRB-approved protocol. Data on file. and its national implementations and are not yet commercially available in the European Union.